In-vitro studies showed that a number of factors are likely to influence the production and maintenance of a bifidobacillary flora and low H in the faeces of newborn infants. Considerable importance is attached to the nature of the end products of bacterial metabolism in the large intestine. Thus, there is evidence to suggest that acetic acid and other metabolites of intraluminal bacterial growth suppress the growth of gram-negative organisms, but are without effect upon that of bifidobacteria. This mechanism in turn is controlled by the nature of the feed; important factors in breast milk include high lactose, low protein and low phosphate content.


Article metrics loading...

Loading full text...

Full text loading...



  1. Beerens H., Schaffner Y., Guillaume J., Castel M. M. 1963; Les bacilles anaerobies non sporules a Gram-negatif favorises par la bile. Leur appartenance au genre Egger-thella (nov. gen.). Annls Inst Pasteur Lille. 14:5
    [Google Scholar]
  2. Bullen C. L., Tearle P. V., Willis A. T. 1976; Bifidobacteria in the intestinal tract of infants: an in-vivo study. J med Microbiol. 9:327
    [Google Scholar]
  3. Cruickshank R., Duguid J. P., Marmion B. P., Swain R. H. A. 1975; Medical microbiology, vol. 2, The practice of medical microbiology. , 12th ed. Edinburgh:88
    [Google Scholar]
  4. Holdeman L. V., Moore W. E. C. 1972; Anaerobe laboratory manual, Viriginia Polytechnic Institute and State University Anaerobe Laboratory. Blacksburg.
    [Google Scholar]
  5. Miles A. A., Misra S. S., Irwin J. O. 1938; The estimation of the bactericidal power of the blood. J Hyg Camb. 38:732
    [Google Scholar]
  6. Oxoid Manual of Culture Media, Ingredients and other Laboratory Services 1973, 3rd ed. London:199
  7. Willis A. T., Bullen C. L., Williams K., Fagg C. G., Bourne A., Vignon M. 1973; Breast milk substitute. A bacteriological study. Br med J. 4:67
    [Google Scholar]

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error