1887

Abstract

Summary

Isolations of reovirus-like agents (rotaviruses) were made from nine of 23 outbreaks of piglet diarrhoea on different farms and from both weaned and unweaned piglets. The viruses were shown to be morphologically and anti-genically similar to the rotaviruses of children and calves. Gnotobiotic piglets given intranasal inoculations of five different isolates developed acute gastroenteritis, and the virus was re-isolated from the faeces or intestinal contents. The piglet virus was not adapted to replicate in cell culture. We conclude that the pig rotavirus is commonly associated with outbreaks of gastroenteritis and is probably an important aetiological factor in this disease.

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1976-05-01
2024-12-14
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References

  1. Bishop R. F., Davidson G. P., Holmes I. H., Ruck B. J. 1973; Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis. Lancet 2:1281
    [Google Scholar]
  2. Bridger J. C., Woode G. N. 1975; Neonatal calf diarrhoea: identification of a reovirus-like agent (rotavirus) in faeces by immunofluorescence and immune electron microscopy. Br. vet. J. 131:528
    [Google Scholar]
  3. Bridger J. C., Woode G. N., Jones J. M., Flewett T. H., Bryden A. S., Davies H. 1975; Transmission of human rotaviruses to gnotobiotic piglets. J. med. Microbiol. 8:565
    [Google Scholar]
  4. Cox R. W., Horne R. W. 1968 Accurate calibration of the magnification of the A.E.I. EM 6B/2 electron microscope using catalase crystals. In 4th Europ. reg. conf, on electron microscopy. edited by Bocciarelli D. S. Rome: p 579
    [Google Scholar]
  5. Davidson G. P., Bishop R. F., Townley R. R. W., Holmes I. H., Ruck B. J. 1975; Importance of a new virus in acute sporadic enteritis in children. Lancet 1:242
    [Google Scholar]
  6. Els H. J., Lecatsas G. 1972; Morphological studies on simian virus S.A. 11 and the “ related ” O agent. J. gen. Virol. 17:129
    [Google Scholar]
  7. Flewett T. H., Bryden A. S., Davies H. 1973; Virus particles in gastroenteritis. Lancet 2:1497
    [Google Scholar]
  8. Flewett T. H., Bryden A. S., Davies H. 1975; Virus diarrhoea in foals and other animals. Vet. Rec. 96:477
    [Google Scholar]
  9. Flewett T. H., Bryden A. S., Davies H., Woode G. N., Bridger J. C., Derrick J. M. 1974; Relation between viruses from acute gastroenteritis of children and new born calves. Lancet 2:61
    [Google Scholar]
  10. Hall G. A., Bridger J. C., Chandler R. L., Woode G. N. 1976; A study of gnotobiotic piglets experimentally infected with the neonatal calf diarrhoea reovirus-like agent (rotavirus). Vet. Path. in press
    [Google Scholar]
  11. Kapikian A. Z., Kim H. W., Wyatt R. G., Rodriguez W. J., Ross S., Cline W. L., Parrott R. H., Chanock R. M. 1974; Reovirus-like agent in stools: association with infantile diarrhoea and development of serologic tests. Science N. Y. 185:1049
    [Google Scholar]
  12. Mebus C. A., Underdahl N. R., Rhodes M. B., Tweehaus H. J. 1969; Calf diarrhoea (scours) reproduced with a virus from a field outbreak. Nebraska Agric. exp. Stat. Res. Bull. 233:1
    [Google Scholar]
  13. Much D. H., Zajac I. 1972; Purification and characterisation of epizootic diarrhoea of infant mice virus. Infect. Immun. 6:1019
    [Google Scholar]
  14. Phillip J. I. H., Cartwright S. F., Scott A. C. 1971; The size and morphology of T.G.E. and vomiting and wasting disease virus of pigs. Vet. Rec. 88:311
    [Google Scholar]
  15. Smith H. W., Jones J. E. T. 1963; Observations in the alimentary tract and its bacterial flora in healthy and diseased pigs. J. Path. Bact. 86:387
    [Google Scholar]
  16. Tajima M. 1970; Morphology of transmissible gastroenteritis virus of pigs. A possible member of coronaviruses. Brief report. Arch. ges. virusforsch. 29:105
    [Google Scholar]
  17. Tavernor W. D., Trexler P. C., Vaughan L. C., Cox J. E., Jones D. G. C. 1971; The production of gnotobiotic piglets and calves by hysterotomy under general anaesthesia. Vet. Rec. 88:10
    [Google Scholar]
  18. Turner A. J., Caple I. W., Craven J. A. 1973; Demonstration of virus particles in intestinal contents of calves with diarrhoea. Aust. vet. J. 49:544
    [Google Scholar]
  19. Woode G. N., Bridger J. C. 1975; Viral enteritis of calves. Vet. Rec. 96:85
    [Google Scholar]
  20. Woode G. N., Bridger J. C., Hall G. A., Dennis M. J. 1974; The isolation of a reovirus-like agent associated with diarrhoea in colostrum-deprived calves in Great Britain. Res. vet. Sci. 16:102
    [Google Scholar]
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