1887

Abstract

SUMMARY

Five ureaplasmas (T-mycoplasmas) of human origin and four of bovine origin were inoculated into the mammary glands of mice. The strains multiplied and neutrophils were observed in sections of infected glands. Some of the glands were macroscopically inflamed, albeit slightly, at necropsy but none of the mice showed any sign of disease during the course of the experiments. All nine ureaplasma strains produced mastitis in BSVS mice and the mammary glands of mice appear more susceptible to ureaplasmas than the udders of cows or goats. Mouse mastitis is suggested as being a suitable small animal model for studying ureaplasma infections.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-8-4-523
1975-11-01
2022-08-13
Loading full text...

Full text loading...

/deliver/fulltext/jmm/8/4/medmicro-8-4-523.html?itemId=/content/journal/jmm/10.1099/00222615-8-4-523&mimeType=html&fmt=ahah

References

  1. Anderson J. C. 1971; Observations on mouse mastitis produced by inoculation of different strains of staphylococcus. Res. vet. Sci 12:186
    [Google Scholar]
  2. Anderson J. C. 1974; Experimental staphylococcal mastitis in the mouse: effects of extracellular products and whole bacterial cells from a high-virulence and a low-virulence strain of Staphylococcus aureus. J. med. Microbiol 7:205
    [Google Scholar]
  3. Anderson J. C., Chandler R. L. 1975; Experimental staphylococcal mastitis in the mouse: histological, ultrastructural and bacteriological changes caused by a virulent strain of Staphylococcus aureus. J. comp. Path (in press)
    [Google Scholar]
  4. Brownlie J., Howard C. J., Gourlay R. N. 1974; Mycoplasmacidal activity of bovine milk for T-mycoplasmas. J. Hyg., Camb 73:415
    [Google Scholar]
  5. Chandler R. L. 1970; Experimental bacterial mastitis in the mouse. J. med. Microbiol 3:273
    [Google Scholar]
  6. Derbyshire J. B., Berman D. T. 1968; Leukocytic responses of the bovine udder to infusion of certain irritants. Am. J. vet. Res 29:1971
    [Google Scholar]
  7. Gourlay R. N., Brownlie J., Howard C. J. 1973; Isolation of T-mycoplasmas from goats, and the production of sub-clinical mastitis in goats by the intramammary inoculation of human T-mycoplasmas. J. gen. Microbiol 76:251
    [Google Scholar]
  8. Gourlay R. N., Howard C. J., Brownlie J. 1972; The production of mastitis in cows by intramammary inoculation of T-mycoplasmas. J. Hyg., Camb 70:511
    [Google Scholar]
  9. Howard C. J., Brownlie J., Gourlay R. N., Collins J. 1975; Presence of a dialysable fraction in normal bovine whey capable of killing several species of bovine mycoplasmas. J. Hyg., Camb 74:261
    [Google Scholar]
  10. Howard C. J., Gourlay R. N., Brownlie J. 1973; The virulence of T-mycoplasmas isolated from various animal species, assayed by intramammary inoculation in cattle. J. Hyg., Camb 71:163
    [Google Scholar]
  11. Shepard M. C., Lunceford C. D., Ford D. K., Purcell R. H., Taylor-Robinson D., Razin S., Black F. T. 1974; Ureaplasma urealyticum gen. nov., sp. nov.: proposed nomenclature for human T (T-strain) mycoplasmas. Int. J. syst. Bact 24:160
    [Google Scholar]
  12. Taylor-Robinson D., Addey J. P., Goodwin C. S. 1969; Comparison of techniques for the isolation of T-strain mycoplasmas. Nature, Lond 222:274
    [Google Scholar]
  13. Taylor-Robinson D., Purcell R. H. 1966; Mycoplasmas of the human urogenital tract and oropharynx and their possible role in disease: a review with some recent observations. Proc. R. Soc. Med 59:1112
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-8-4-523
Loading
/content/journal/jmm/10.1099/00222615-8-4-523
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error