1887

Abstract

SUMMARY

Sheep were experimentally infected with serotype and after 34 days the kidneys were examined by electron microscopy. Colonisation of the kidneys was well established at this time and changes in the kidney tubules included a concentration of leptospires around the periphery of the proximal tubular lumen. The microvilli making up the brush border were in some instances greatly reduced in numbers and in others the microvilli had developed bulbous ends. Necrotic epithelial cells within the tubules were observed and these were sometimes found free in the tubular lumen. The possible sequence of events leading to these changes is discussed.

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/content/journal/jmm/10.1099/00222615-7-4-505
1974-11-01
2024-12-08
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References

  1. Brito T. De, Freymuller E., Hoshino S., and Penna D. O. 1966; Pathology of the kidney and liver in the experimental leptospirosis of the guinea-pig. Virchows Arch. path. Amt. Physiol 341:64
    [Google Scholar]
  2. Brito T. De, Freymuller E., Penna D. O., Santos H. S., Soares de Almeida S., Ayroza Galvao P. A., Pereira V. C. 1965; Electron microscopy of the biopsied kidney in human leptospirosis. Am. J. Trop. Med. Hyg 14:397
    [Google Scholar]
  3. Brito T. D., Penna D. O., Perebra V. C., Hoshino S. 1967; Kidney biopsies in human leptospirosis: a biochemical and electron microscopy study. Virchows Arch. path. Amt. Physiol 343:124
    [Google Scholar]
  4. Chatelanat F., Simon G. T. 1969; Ultrastructural pathology of the tubules and interstitial tisue. In The kidney edited by Rouiller C. Muller A. F. New York and London: vol 1: p 495
    [Google Scholar]
  5. Harrington D. D., Sleight S. D. 1966; Leptospira pomona in tissue culture: preliminary study. Am. J. vet. Res 27:249
    [Google Scholar]
  6. Hartley W. J. 1952; Ovine leptospirosis. Aust. vet. J 28:169
    [Google Scholar]
  7. Martino C. De, Bruni C. B., Bellocci M., Natali P. G. 1969; Spontaneous lepto-spiral infection of the rat kidney: an ultrastructural study. Exp. molec. Path 10:27
    [Google Scholar]
  8. Miller N. G., Wilson R. B. 1966; Electron microscopy of the liver of the hamster during acute and chronic leptospirosis. Am. J. vet. Res 27:1071
    [Google Scholar]
  9. Sitprija V., Evans H. 1970; The kidney in human leptospirosis. Am. J. Med 49:780
    [Google Scholar]
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