1887

Abstract

SUMMARY

Sera from patients who had undergone open-heart surgery were examined for antibodies to by counter-immunoelectrophoresis, immuno-diffusion, immunofluorescence, and agglutination tests. No single test gave an absolute indication of systemic infection or endocarditis, although the immuno-diffusion procedure was the most specific test. A counter-immunoelectrophoresis test is recommended as a screening procedure, provided that positive results are confirmed by other techniques.

Postive serological findings in the absence of clinical endocarditis is probably due to transient fungaemia but should alert the clinician to the possibility that endocarditis may develop later. Serological monitoring should be continued for at least 3 years after cardiac surgery.

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/content/journal/jmm/10.1099/00222615-7-4-415
1974-11-01
2020-01-28
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