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Broth cultures of 24 out of 28 urease-positive strains of Clostridium sordellii tested lysed readily when mitomycin C (MC) was added early in the logarithmic phase of growth. Toxigenic strains of the species were more susceptible than the non-toxigenic strains to the effect of the drug. Phage-like particles with different morphologies could be obtained from cultures of all of five C. sordellii strains studied. The lytic agent or agents active on freeze-thawed cells of C. sordellii strains were also found in the MC lysates.
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