Depression of Lactase Activity in the Small Intestine of Infant Rabbits by Free

Abstract

SUMMARY

Strains of isolated from the duodenum of infants with acute gastro-enteritis were inoculated into ligated segments of small intestine of infant rabbits. Twenty hours later, the lactase activity in the mucosa of these segments was compared with the lactase activity in similar segments into which sterile broth had been inoculated. Analysis of the results from 25 matched pairs of loops showed a statistically significant decrease in lactase activity in the loops that had received . We suggest that the depression of lactase activity observed in infants with gastro-enteritis may be caused or perpetuated by the growth of in the duodenum.

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/content/journal/jmm/10.1099/00222615-7-2-259
1974-05-01
2024-03-28
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References

  1. Barnes G. L., Bishop R. F., Townley R. R. W. 1973; Microbial flora and disac-charidase depression in infantile gastroenteritis. Unpublished observations
    [Google Scholar]
  2. Bishop R. F., Barnes G. L., Townley R. R. W. 1973; Microbial flora of stomach and small intestine in infantile gastroenteritis. Unpublished observations
    [Google Scholar]
  3. Burrows W., Musteikis G. M. 1966; Cholera infection and toxin in the rabbit ileal loop. J. infect. Dis 116:183
    [Google Scholar]
  4. Cregan J., Hayward N. J. 1953; The bacterial content of the healthy human small intestine. Br. med. J 1:1356
    [Google Scholar]
  5. Dahlqvist A. 1964; Method for assay of intestinal disaccharidases. Analyt. Biochem 7:18
    [Google Scholar]
  6. Doell R. G., Kretchmer N. 1962; Studies of small intestine during development. Distribution and activity of β-galactosidase. Biochem. biophys. Acts 62:353
    [Google Scholar]
  7. Iwata K., Uchida F. 1969; Canditoxin, a new toxic substance from a strain of Candida albicans. Antonie van Leeuwenhoek 35: Suppl. E39
    [Google Scholar]
  8. Kozinn P. J., Taschdjian C. L. 1962; Enteric candidiasis. Diagnosis and clinical considerations. Pediatrics, Springfield 30:71
    [Google Scholar]
  9. Moon H. W., Whipp S. C. 1971; Systems for testing the enteropathogenicity of Escherichia coli. Ann. N. Y. Acad. Sci 176:197
    [Google Scholar]
  10. Rogers K. B. 1966; Candida infections in paediatrics. In Symposium on Candida infections, edited by H. I. Winner and R. Hurley. London p 179
    [Google Scholar]
  11. Smith H. W. 1965; The development of the flora of the alimentary tract in young animals. J.Path. Bact 90:495
    [Google Scholar]
  12. Smith H. W., Gyles C. L. 1970; The effect of cell-free fluids prepared from cultures of human and animal enteropathogenic strains of Escherichia coli on ligated intestinal segments of rabbits and pigs. J. med. Microbiol 3:403
    [Google Scholar]
  13. Winner H. I., Hurley R. 1964 Candida albicans London: p 212
    [Google Scholar]
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