1887

Abstract

SUMMARY

The changes that occurred in the faecal flora during the separate administration of lactulose and magnesium sulphate were studied in five patients with hepatic encephalopathy. Lactulose therapy produced significant increases in lactobacillus counts in three patients, and two of these patients showed clinical improvement. No systematic change occurred in the counts of other organisms during either treatment; in particular it was not possible to correlate clinical improvement with a reduction in the count of the two groups of organisms-enterobacteria and spp.-that are considered to be most active in the production of ammonia.

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/content/journal/jmm/10.1099/00222615-7-2-163
1974-05-01
2022-08-11
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References

  1. Bircher J., Scollo-Lavizzari G., Hoffmann K., Haemmerli U. P. 1969; Die Behandlung der chronischen porto-systemischen Enzephalopathie mit Laktulose. Schwiez. med. Wschr 99:584
    [Google Scholar]
  2. Conn H. O., Floch M. H. 1970; Effects of lactulose and Lactobacillus acidophilus on the faecal flora. Am. J. clin. Nutr 23:1588
    [Google Scholar]
  3. Dahlqvist A., Gryboski J. D. 1965; Inability of human small-intestinal lactase to hydrolyse lactulose. Biochim. biophys. Acta 110:635
    [Google Scholar]
  4. Elkington S. G., Floch M. H., Conn H. O. 1969; Control of chronic portalsystemic encephalopathy by lactulose. Gut 10:416
    [Google Scholar]
  5. Fung W. P., Khoo O. T. 1968; Treatment of chronic hepatic encephalopathy with lactulose. Med. J. Aust 2:160
    [Google Scholar]
  6. Goldsmith P. L. 1965 Programme modification Program ICI/A/10705/9, ICI Computer Library
    [Google Scholar]
  7. Haenel H., Feldheim W., Muller-Beuthow W., Ruttloff H. 1958; Versuche zur Umstimmung der faecalen Flora des gesunden Erwachsenen. Zentbl. Bakt. ParasitKde 1 Abt. Orig 173:76
    [Google Scholar]
  8. Haenel H., Muller-Beuthow W., Scheunert A. 1957; Der Einfluss extremer Kostformen auf die faecale Flora des Menschen. II. Mitterlung. Zentbl. Bakt. ParasitKde 1 Abt. Orig 169:45
    [Google Scholar]
  9. Hamilton J. D., Dyer N. H., Dawson A. M., O’Grady F. W., Vince A., Fenton J. C. B., Mollin D. L. 1970; Assessment and significance of bacterial overgrowth in the small bowel. Q. Jl Med 39:265
    [Google Scholar]
  10. Hoffmann K., Mossel D. A. A., Korus W., Kamer J. H. Van De. 1964; Unter-suchungen uber die Wirkungsweise der Lactulose (jS-Galactosido-Fructose) im Darm. Klin. Wschr 42:126
    [Google Scholar]
  11. Ma M. H., McLeod J. G., Blackburn C. R. B. 1969; Long term treatment of chronic portal systemic encephalopathy with lactulose. Australas. Ann. Med 18:117
    [Google Scholar]
  12. O’Grady F. W. 1966; Differences in ammonia production by faecal bacteria of patients with hepatic encephalopathy. Proc. R. Soc. Med 59:1246
    [Google Scholar]
  13. Zeegen R., Drinkwater J. E., Fenton J. C. B., Vince A., Dawson A. M. 1970; Some observations on the effects of treatment with lactulose on patients with chronic hepatic encephalopathy. Q. J Med 39:245
    [Google Scholar]
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