RT Journal Article SR Electronic(1) A1 Linton, K. B. A1 Richmond, M. H. A1 Bevan, Rosemary A1 Gillespie, W. A.YR 1974 T1 Antibiotic Resistance and R Factors in Coliform Bacilli Isolated from Hospital and Domestic Sewage JF Journal of Medical Microbiology, VO 7 IS 1 SP 91 OP 103 DO https://doi.org/10.1099/00222615-7-1-91 PB Microbiology Society, SN 1473-5644, AB SUMMARY One-hundred and one samples from a wide variety of sewers and water-drainage channels in Bristol, including some sewers that separately drained hospital and domestic premises, were examined for antibiotic-resistant coliform bacilli and for R factors. The antibiotic-sensitivity patterns of over 3000 coliform bacilli isolated were obtained and 1000 resistant strains were tested for R-factor transfer. Hospital sewage contained more coliform bacilli with much higher proportions of resistant bacteria, more R factors, and a greater proportion of R factors carrying multiple resistance, than sewage from domestic and other sources. Despite these findings, it was calculated that less than 5% of the R factors in the sewage output of the City of Bristol originate in hospitals. The normal, healthy population appears to be by far the greatest reservoir of R factors in the community., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-7-1-91