1887

Abstract

SUMMARY

Cell-free extracts of adenovirus-12-induced tumours were used to immunise CBA mice against transplantation of the homologous tumour cells. Greater immunity was obtained when heat-killed was added to the tumour extract. Less conclusive results were obtained with . In contrast, tumour cell extract plus or gave significantly less immunity than did the tumour extract alone. and had no effect on immunity to tumour challenge.

The enhancement or depression of immunity appeared to operate through cellular rather than humoral or antibody mechanisms.

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/content/journal/jmm/10.1099/00222615-7-1-17
1974-02-01
2022-08-16
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