A Rapid Method of Assaying Gentamicin and Kanamycin Concentrations in Serum Free

Abstract

SUMMARY

A simple method is described for the assay of gentamicin and kanamycin in human serum. It is a modification of the monosaccharide hydrolysis method of Faine and Knight (1968) and will estimate low concentrations of antibiotic accurately within 3 hours. The method gives results similar to those obtained by a double-row tube-dilution growth inhibition technique, is unaffected by the presence of penicillins or cephalosporins, and requires only standard laboratory equipment. Because the method gives readily reproducible results and is easy to perform, it should commend itself to all laboratories dealing with patients receiving aminoglycoside therapy.

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/content/journal/jmm/10.1099/00222615-7-1-11
1974-02-01
2024-03-29
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