1887

Abstract

SUMMARY

A plasmid (PF) has been identified in 18 strains of that belong to phage-groups I, II, and III or are non-typable. This plasmid is characterised by: () carrying the genes for resistance to fusidic acid and cadmium ions, but not to arsenate or mercury ions, and for the production of D-serotype penicillinase, () A molecular weight of 16 million daltons, () the ability to exist with a “penicillinase plasmid” of compatibility-group I, and () a tendency to fragment. The PF plasmid has probably spread among the natural population of staphylococci.

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1974-02-01
2022-01-23
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References

  1. Asheshov E. H. 1969; The genetics of penicillinase production in Staphylococcus aureus PS80. J. gen. Microbiol 59:289
    [Google Scholar]
  2. Asheshov E. H., Rippon J. 1959; Changes in typing pattern of phage type 80 staphylococci. J. gen. Microbiol 20:634
    [Google Scholar]
  3. Dyke K. G. H., Parker M. T., Richmond M. H. 1970; Penicillinase production and metal-ion resistance in Staphylococcus aureus cultures isolated from hospital patients. J. med. Microbiol 3:125
    [Google Scholar]
  4. Evans R. J., Water worth P. M. 1966; Naturally-occurring fusidic acid resistance in staphylococci and its linkage to other resistances. J. clin. Path 19:555
    [Google Scholar]
  5. Jessen O., Rosendal K., Bulow P., Faber V., Eriksen K. R. 1969; Changing staphylococci and staphylococcal infections: a ten-year study of bacteria and cases of bacteremia. New Engl. J. Med 281:627
    [Google Scholar]
  6. Jevons M., John M., Parker M. T. 1966; Cultural characters of a newly recognised group of hospital staphylococci. J. clin. Path 19:305
    [Google Scholar]
  7. Lacey R. W. 1972; Genetic control in methicillin-resistant strains of Staphylococcus aureus. J. med. Microbiol. 5:497
    [Google Scholar]
  8. Lacey R. W., Grinsted J. 1972; Linkage of fusidic acid resistance to the penicillinase plasmid in Staphylococcus aureus. J. gen. Microbiol 73:501
    [Google Scholar]
  9. Lacey R. W., Grinsted J. 1973; Genetic analysis of methicillin-resistant strains of Staphylococcus aureus’, evidence for their evolution from a single clone. J. med. Microbiol 6:511
    [Google Scholar]
  10. Lowbury E. J. L., Hood A. M. 1953; The acquired resistance of Staph, aureus to bacteriophage. J. gen. Microbiol 9:524
    [Google Scholar]
  11. Novick R. P. 1963; Analysis by transduction of mutations affecting penicillinase formation in Staphylococcus aureus. J. gen. Microbiol 33:121
    [Google Scholar]
  12. Novick R. P. 1967; Penicillinase plasmids of Staphylococcus aureus. Fedn. Proc 26:29
    [Google Scholar]
  13. Novick R. P., Morse S. I. 1967; In vivo transmission of drug resistance factors between strains of Staphylococcus aureus. J. exp. Med 125:45
    [Google Scholar]
  14. Parker M. T., Hewitt J. H. 1970; Methicillin resistance in Staphylococcus aureus. Lancet 1:800
    [Google Scholar]
  15. Richmond M. H. 1965; Wild-type variants of exopenicillinase from Staphylococcus aureus. Biochem. J. 94:584
    [Google Scholar]
  16. Richmond M. H. 1967; A second regulatory region involved in penicillinase synthesis in Staphylococcus aureus. J. molec. Biol 26:357
    [Google Scholar]
  17. Richmond M. H. 1969; Extrachromosomal elements and the spread of antibiotic resistance in bacteria. Biochem. J 113:225
    [Google Scholar]
  18. Richmond M. H., Johnson J. 1969; The reversible transition of certain genes in Staphylococcus aureus between the integrated and the extrachromosomal state. Genet. Res. 13:267
    [Google Scholar]
  19. Richmond M. H., Parker M. T., Jevons M. P., John M. 1964; High penicillinase production correlated with multiple antibiotic resistance in Staphylococcus aureus. Lancet 1:293
    [Google Scholar]
  20. Rosdahl V. T. 1973; Naturally-occurring constitutive β-lactamase of novel serotype in Staphylococcus aureus. J. gen. Microbiol 77:229
    [Google Scholar]
  21. Rosendal K., Bulow P. 1965; Temperate phages influencing lipase production by Staphylococcus aureus. J. gen. Microbiol. 41:349
    [Google Scholar]
  22. Rountree P. M. 1959; Changes in the phage-typing patterns of staphylococci following lysogenization. J. gen. Microbiol. 20:620
    [Google Scholar]
  23. Wright G. L. T., Harper J. 1970; Fusidic acid and lincomycin therapy in staphylococcal infections in cystic fibrosis. Lancet 1:9
    [Google Scholar]
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