resembled in being able to sensitise mice to histamine. Strains of mice that were strongly sensitised to histamine by were also strongly sensitised by , whereas mouse strains that did not respond to were refractory to sensitisation by Other similarities between sensitisation produced by the two organisms included a dependence on mouse age and a tendency in some strains to produce a bimodal response to histamine following sensitisation. Both and were capable of sensitising mice of one strain to serotonin, but sensitisation of another mouse strain to serotonin was produced only by and not by

Unlike did not augment anaphylaxis to heterologous antigens, nor did it produce leucocytosis and lymphocytosis in mice. Preliminary studies of the stability of the sensitising agent suggest that it is chemically different from the histamine-sensitising factor of


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