1887

Abstract

Summary

After being given tetracycline in drinking water (0·1 per cent.) for 5 days, rats were inoculated orally with on three occasions at 2-day intervals. Immediately after the first inoculation, the concentration of tetracycline in the water was reduced to 0·01 per cent. and this was maintained for the next 28 days. The rats' mouths were regularly colonised by , the organism being recoverable throughout the experiment. Histological examination showed the organism in the tissues in 75 per cent. of the animals. Infection of the dorsal surface of the tongue produced a striking change in the histological appearance of the lingual epithelium, reminiscent of that found in candidal leukoplakia in man.

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/content/journal/jmm/10.1099/00222615-6-3-275
1973-08-01
2019-10-20
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-6-3-275
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