RT Journal Article SR Electronic(1) A1 Kronvall, G.YR 1973 T1 A Rapid Slide-Agglutination Method for Typing Pneumococci by Means of Specific Antibody Adsorbed to Protein A-Containing Staphylococci JF Journal of Medical Microbiology, VO 6 IS 2 SP 187 OP 190 DO https://doi.org/10.1099/00222615-6-2-187 PB Microbiology Society, SN 1473-5644, AB SUMMARY A new slide-agglutination method was developed for the serological typing of pneumococci. Type-specific antibodies were bound to stabilised, protein-A containing staphylococci through theri Fc fragments. The combining sites of the antibodies remained available to the corresponding type-specific antigen; when pneumococci were mixed with a suspension of the stabilised staphylococci coated with homologous antibody, strong agglutination occurred rapidly. Eighty-nine pneumococcal strains were typed by this agglutination method. The results obtained were in complete agreement with those of typing by Neufeld’s capsule-“ swelling” method., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-6-2-187