1887

Abstract

Summary

Specimens from 466 patients with acute respiratory-tract illnesses that failed to yield a causative agent by the standard methods of virus isolation were examined in organ cultures. Seventy-three viruses (15·7 per cent) were isolated. Most of them were rhinoviruses (81·0 per cent.) but seven coronaviruses, four of which were 229E-like, were also isolated. The majority of the rhinoviruses were detected in the initial organ-culture fluids, but several blind passages were needed for the organ-culture strains of coronaviruses. Although laborious, organ culture must remain an integral part of any detailed study of acute infections of the respiratory tract.

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/content/journal/jmm/10.1099/00222615-6-2-177
1973-05-01
2019-09-16
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-6-2-177
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