1887

Abstract

SUMMARY

Rubella virus possesses inherent photosensitivity and slowly loses infectivity when exposed to light. Sensitisation with proflavine markedly increases the rate of photoinactivation, and loss of infectivity, without loss of haemagglutinin activity, is most readily achieved at 9.0. Photodynamically inactivated rubella virus stimulates HI antibody formation in monkeys.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-5-4-515
1972-11-01
2022-08-14
Loading full text...

Full text loading...

/deliver/fulltext/jmm/5/4/medmicro-5-4-515.html?itemId=/content/journal/jmm/10.1099/00222615-5-4-515&mimeType=html&fmt=ahah

References

  1. Appleyard G. 1967; The photosensitivity of Semliki Forest andother viruses. J. Gen. Virol 1:143
    [Google Scholar]
  2. Beck E. S. 1969; Review of studies with inactivated rubella virus. Amer. J. Dis. Child 118:328
    [Google Scholar]
  3. Borgen H. C., Espensen L. 1970; Immunizing effect of photoinactivated pseudorabies virus. Zentbl. Bakt. ParasitKde I. Abt. Orig 214:13
    [Google Scholar]
  4. Chessin M. 1960; Photodynamic inactivation of infectious nucleic acid. Science, N.Y 132:1840
    [Google Scholar]
  5. Content J., Cogniaux-leclerc Jacqueline. 1968; Comparison of the in vitro action of ethidium chloride on animal viruses with that of other photodyes. J. Gen. Virol 3:63
    [Google Scholar]
  6. Crawford J. G., Dayhuff T. R. 1968; Hog cholera: preparation of hog cholera immunogen from photodynamically inactivated virus. Amer. J. Vet. Res 29:1741
    [Google Scholar]
  7. Crawford J. G., Dayhuff T. R., White E. A. 1968; Hog cholera: safety and protection studies with photodynamically inactivated hog cholera virus. Amer. J. Vet. Res 29:1749
    [Google Scholar]
  8. Crawford J. G., White E. A., Dayhuff T. R. 1968; Hog cholera: response of pigs vaccinated under field conditions with photodynamically inactivated hog cholera vaccine of tissue culture origin. Amer. J. Vet. Res 29:1761
    [Google Scholar]
  9. Crowther D., Melnick J. L. 1961; The incorporation of neutral red and acridine orange into developing poliovirus particles making them photosensitive. Virology 14:11
    [Google Scholar]
  10. Cutchins E. C., Dayhuff T. R. 1962; Photoinactivation of measles virus. Virology 17:420
    [Google Scholar]
  11. Dempsey T. F., Meyer V. 1934; Canine distemper vaccine. Two experiments with vaccine prepared by photodynamic inactivation of thevirus with methylene blue. J. Comp. Path. Ther 47:197
    [Google Scholar]
  12. Frank G. H., Foster J. W. 1967; Photodynamic inactivation of Newcastle disease virus with acridine orange. Appl. Microbiol 15:1452
    [Google Scholar]
  13. Frankel J. W. 1964; Neutralizing antibody responses of guinea-pigs to inactivated rubella virus vaccine. Nature, Lond 204:655
    [Google Scholar]
  14. Fukunaga T., Ishikawa N., Igarashi A., Fukai K. 1967; Photodynamic inactivation of Japanese encephalitis virus. Biken J 10:1
    [Google Scholar]
  15. Hackett A. J. 1962; The photodynamic effects of acridine orange on an RNA virus (vesicular exanthema). Photochem. Photobiol 1:147
    [Google Scholar]
  16. Harrison A. P., Raabe V. A., Brummett G. H. 1968; Detection of in vivo protein photooxidation by means of tritium loss from the histidine moieties. Proc. Soc. Exp. Biol. Med 127:538
    [Google Scholar]
  17. Hiatt C. W. 1960; Photodynamic inactivation of viruses. Trans. N.Y. Acad. Sci 23:66
    [Google Scholar]
  18. Hilleman M. R., Buynak E. B., Weibel R. E., Stokes J. Jr 1968; Live, attentuated rubella-virus vaccine. New Engl. J. Med 279:300
    [Google Scholar]
  19. Kaplan C. 1969; Immunization against smallpox. Br. Med. Bull 25:131
    [Google Scholar]
  20. Meyer H. M. Jr, Parkman P. D. 1967; Rubella: epidemiology, virology and immunology. III. The immunology of rubella. Amer. J. Med. Sci 253:364
    [Google Scholar]
  21. Nemo G. J., Cutchins E. C. 1966; Effects of visible light on canine distemper virus. J. Bad 91:798
    [Google Scholar]
  22. Oster G., Mclaren A. D. 1950; The ultraviolet light and photosensitized inactivation of tobacco mosaic virus. J. Gen. Physiol 33:215
    [Google Scholar]
  23. Perdrau J. R., Todd C. R. 1933a; The photodynamic action of methylene blue on certain viruses. Proc. Roy. Soc B 112:288
    [Google Scholar]
  24. Perdrau J. R., Todd C. 1933b; Canine distemper. The high antigenic value of the virus after photodynamic inactivation by methylene blue. J. Comp. Path. Ther 46:78
    [Google Scholar]
  25. Reed L. J., Muench H. 1938; A simple method of estimating fifty per cent, endpoints. Amer. J. Hyg 27:493
    [Google Scholar]
  26. Schaffer F. L. 1962; Binding of proflavine by and photoinactivation of poliovirus propagated in the presence of the dye. Virology 18:412
    [Google Scholar]
  27. Schmidt N. J., Lennette E. H., Gee P. S., Dennis J. 1968; Physical and immunologic properties of rubella antigens. J. Immun 100:851
    [Google Scholar]
  28. Sever J. L., Schiff G. M., Huebner R. J. 1963; Inactivated rubella virus vaccine. J. Lab. Clin. Med 62:1015
    [Google Scholar]
  29. Skinner H. H., Bradish C. J. 1954; Exposure to light as a source of error in the estimation of the infectivity of virus suspensions. J. Gen. Microbiol 10:377
    [Google Scholar]
  30. Sluyterman L. A. AE. 1962; Photo-oxidation, sensitized by proflavine,of a number of protein constituents. Biochim. biophys. acta 60:557
    [Google Scholar]
  31. Sprecher-goldberger S. 1965; Photosensitization of RNA viruses by ethidium chloride. Acta virol, Prague 9:385
    [Google Scholar]
  32. Stewart G. L., Parkman P. D., Hopps H. E., Douglas R. D., Hamilton J. P., Meyer H. M. 1967; Rubella-virus hemagglutination-inhibition test. New Engl. J. Med 276:554
    [Google Scholar]
  33. Tomita T., Prince A. M. 1963; Photodynamic inactivation of arbor virusesby neutral red and visible light. Proc. Soc. Exp. Biol. Med 112:887
    [Google Scholar]
  34. Turner G. S., Kaplan C. 1965; Observations on photodynamic inactivation of vaccinia virus and its effect on immunogenicity. J. Hyg., Camb 63:395
    [Google Scholar]
  35. Turner G. S., Kaplan C. 1968; Photoinactivation of vaccinia virus with rose bengal. J. Gen. Virol 3:433
    [Google Scholar]
  36. Wallis C., Melnick J. L. 1964; Irreversible photosensitization of viruses. Virology 23:520
    [Google Scholar]
  37. Wallis C., Melnick J. L. 1965; Photodynamic inactivation of animal viruses: a review. Photochem. Photobiol 4:159
    [Google Scholar]
  38. Wallis C., Sakurada N., Melnick J. L. 1963; Influenza vaccine prepared by photo-dynamic inactivation of virus. J. Immun 91:677
    [Google Scholar]
  39. Wallis C., Scheiris Charlotte, Melnick J. L. 1967; Photodynamically inactivated vaccines prepared by growing viruses in cells containing neutral red. J. Immun 99:1134
    [Google Scholar]
  40. Wallis C., Trulock S., Melnick J. L. 1969; Inherent photosensitivity of herpes virus and other enveloped viruses. J. Gen. Virol 5:53
    [Google Scholar]
  41. Weil L., Gordon W. G., Buchert A. R. 1951; Photooxidation of amino acids in the presence of methylene blue. Archs Biochem. Biophys 33:90
    [Google Scholar]
  42. Weil L., James S., Buchert A. R. 1953; Photooxidation of crystalline chymotrypsinin the presence of methylene blue. Archs Biochem. Biophys 46:266
    [Google Scholar]
  43. Weil L., Seibles T. S. 1955; Photooxidation of crystalline ribonuclease in the presence of methylene blue. Archs Biochem. Biophys 54:368
    [Google Scholar]
  44. Welsh J. N., Adams M. H. 1954; Photodynamic inactivation of bacteriophage. J. Bact 68:122
    [Google Scholar]
  45. Wilson J. N., Cooper P. D. 1963; Aspects of the growth of poliovirus as revealed by the photodynamic effects of neutral red and acridine orange. Virology 21:135
    [Google Scholar]
  46. Yamamoto N. 1956; Photodynamic action on bacteriophage. I. The relation between the chemical structure and the photodynamic activity of various dyes. Virus 6:510
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-5-4-515
Loading
/content/journal/jmm/10.1099/00222615-5-4-515
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error