Photodynamic Inactivation Of Rubella Virus

Rubella virus possesses inherent photosensitivity and slowly loses infectivity when exposed to light. Sensitisation with proflavine markedly increases the rate of photoinactivation, and loss of infectivity, without loss of haemagglutinin activity, is most readily achieved at pH 9·0. Photodynamically inactivated rubella virus stimulates HI antibody formation in monkeys.