1887

Abstract

Summary

A substance with the characteristics of a specific antibody was found in immune guineapig sera. It had inhibitory activity towards the growth of promastigotes and cytotoxicity to the amastigote form of . The inhibitory effect was shown by direct counting of viable leptomonads. The cytotoxicity of immune sera on amastigotes was evaluated on the basis of morphological changes as well as of a decrease in the number of the organisms. The substance responsible was found to be heat stable and complement dependent. The activity could be removed by the specific absorption.

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/content/journal/jmm/10.1099/00222615-5-3-371
1972-08-01
2023-02-01
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