1887

Abstract

Summary

Strains of K12F to which Ent plasmids from a human and a porcine enteropathogenic strain of had been transmitted yielded cellfree preparations that produced diarrhoea when administered orally to baby rabbits. The preparations obtained from the strain containing the “porcine” plasmid was more active in this respect than were those of the strain containing the “human” plasmid. This difference was also observed when preparations of wild human and porcine enteropathogenic strains were compared. The diarrhoea produced in the baby rabbits resembled that produced by enterotoxin.

The diarrhoea-producing activity of cell-free preparations of the K12 strain that contained the “porcine” Ent plasmid could be neutralised by antiserum against either this strain or ; so could cell-free preparations of , but more heterologous than homologous antiserum was required in each case to achieve neutralisation.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-5-3-299
1972-08-01
2024-04-25
Loading full text...

Full text loading...

/deliver/fulltext/jmm/5/3/medmicro-5-3-299.html?itemId=/content/journal/jmm/10.1099/00222615-5-3-299&mimeType=html&fmt=ahah

References

  1. Dutta N. K., Panse M. V., Kulkarni D. R. 1959; Role of cholera toxin in experimental cholera. J. Bact 78:594
    [Google Scholar]
  2. Gyles C. L., Barnum D. A. 1969; A heat-labile enterotoxin from strains of Escherichia coli enteropathogenic for pigs. J. Infect. Dis 120:419
    [Google Scholar]
  3. Kohler E. M. 1968; Enterotoxin activity of filtrates of Escherichia cotli in young pigs. Amer. J. Vet. Res 29:2263
    [Google Scholar]
  4. Smith H. W., Gyles C. L. 1970a; The relationship between two apparently different enterotoxins produced by enteropathogenic strains of Escherichia cotli of porcine origin. J. Med. Microbiol 3:387
    [Google Scholar]
  5. Smith H. W., Gyles C. L. 1970b; The effect of cell-free fluids prepared from cultures of human and animal enteropathogenic strains of Escherichia cotli on ligated intestinal segments of rabbits and pigs. J. Med. Microbiol 3:403
    [Google Scholar]
  6. Smith H. W., Halls Sheila. 1968; The transmissible nature of the genetic factor in Escherichia cotli that controls enterotoxin production. J. Gen. Microbiol 52:318
    [Google Scholar]
  7. Smith H. W., Linggood Margaret A. 1971; The transmissible nature of enterotoxin production in a human enteropathogenic strain of Escherichia coli. J. Med. Microbiol 4:301
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-5-3-299
Loading
/content/journal/jmm/10.1099/00222615-5-3-299
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error