@article{mbs:/content/journal/jmm/10.1099/00222615-5-3-275, author = "Tzannetis, S. E. and Papavassiliou, J. and Papanayiotou, P.", title = "Naturally Occurring Antibodies Against Colicines In Human Sera", journal= "Journal of Medical Microbiology", year = "1972", volume = "5", number = "3", pages = "275-281", doi = "https://doi.org/10.1099/00222615-5-3-275", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-5-3-275", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "Summary Of 21 human sera from elderly bacteriuric and non-bacteriuric subjects, 12 exerted a significant neutralising activity against 18 type-colicines. The presence of precipitins was demonstrated in five out of the 21 sera. Sera from 20 healthy young adults contained neither neutralising antibodies nor precipitins against type-colicines. The mode of immunisation via the gut and the probable factors influencing this mechanism are discussed. There was no evidence of immunisation via the infected urinary tract in older bacteriuric subjects.", }