1887

Abstract

The natural antibiotic susceptibility of 38 , 35 , 23 and 20 strains was examined. MIC values were determined by a microdilution procedure and evaluated by a table calculation programme. was the least susceptible sp. and was naturally resistant to tetracyclines, some penicillins, older cephalosporins, sulphamethoxazole and fosfomycin and to antibiotics to which other species of Enterobacteriaceae are also resistant. It was naturally sensitive to modern penicillins and cephalosporins, carbapenems and aztreonam, but its susceptibility to aminoglycosides and quinolones was difficult to assess. and strains were the most susceptible spp. They were naturally sensitive or intermediate to tetracyclines and sensitive to aminoglycosides and quinolones. Susceptibility to sparfloxacin, biapenem and sulphamethoxazole permitted the discrimination of and strains. The natural antibiotic susceptibility of strains was between that of and that of the other providenciae. was resistant to tetracyclines and fosfomycin, but more susceptible to aminoglycosides, quinolones, fosfomycin and numerous β-lactam antibiotics than . A database is described of the natural antibiotic susceptibilities of spp. It can be used for the validation of antibiotic susceptibility test results of these micro-organisms.

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1998-07-01
2024-04-24
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References

  1. Hawkey P. M. Providencia stuartii: a review of a multiply antibiotic-resistant bacterium. J Antimicrob Chemother 1984; 13:209–226
    [Google Scholar]
  2. Rinker A. G., Boyd A. L., Gary N. D., Kundig W. Isolation of multiple antibiotic resistant Enterobacteriaceae from river water. Microbios 1988; 56:169–175
    [Google Scholar]
  3. Ladds P. W., Bradley J., Hirst R. G. Providencia rettgeri meningitis in hatchling saltwater crocodiles (Crocodylus porosus). Aust Vet J 1996; 74:397–398
    [Google Scholar]
  4. Albert M. J., Alam K., Ansaruzzaman M. Pathogenesis of Providencia alcalifaciens-induced diarrhea. Infect Immun 1992; 60:5017–5024
    [Google Scholar]
  5. Guth B. E. C., Perrella E. Prevalence of invasive ability and other virulence-associated characteristics in Providencia alcalifaciens strains isolated in Sao Paulo, Brazil. J Med Microbiol 1996; 45:459–462
    [Google Scholar]
  6. Haynes J., Hawkey P. M. Providencia alcalifaciens and travellers’ diarrhoea. BMJ 1989; 299:94–95
    [Google Scholar]
  7. Picard B., Picard-Pasquier N., Krishnamoorthy R., Goullet P. Correlation between DNA polymorphism and enzyme polymorphism argues in favour of the delineation of two species within Providencia alcalifaciens. Res Microbiol 1991; 142:965–969
    [Google Scholar]
  8. Hickman-Brenner F. W., Farmer J. J., Steigerwalt A. G., Brenner D. J. Providencia rustigianii: a new species in the family Enterobacteriaceae formerly known as Providencia alcalifaciens biogroup 3. J Clin Microbiol 1983; 17:1057–1060
    [Google Scholar]
  9. Costas M., Holmes B., Sloss L. L. Numerical analysis of electrophoretic protein patterns of Providencia rustigianii strains from human diarrhoea and other sources. J Appl Bacteriol 1987; 63:319–328
    [Google Scholar]
  10. Müller H. E., O’Hara C. M., Fanning G. R., Hickman-Brenner F. W., Swenson J. M., Brenner D. J. Providencia heimbachae, a new species of Enterobacteriaceae isolated from animals. Int J Syst Bacteriol 1986; 36:252–256
    [Google Scholar]
  11. Penner J. L. The genera Proteus, Providencia, and Morganella. In Balows A., Truper G. G., Dworkin M., Harder W., Schleifer K. H. (eds) The Prokaryotes: a handbook on the biology of bacteria: ecophysiology, isolation, identification, applications New York: Springer-Verlag; 19922849–2862
    [Google Scholar]
  12. Comaglia G., Frugoni S., Mazzariol A., Piacentini E., Berlusconi A., Fontana R. Activities of oral antibiotics on Providencia strains isolated from institutionalized elderly patients with urinary tract infections. Antimicrob Agents Chemother 1995; 39:2819–2821
    [Google Scholar]
  13. Lindsey J. O., Martin W. T., Sonnenwirth A. C., Bennet J. V. An outbreak of nosocomial Proteus rettgeri urinary tract infection. Am J Epidemiol 1976; 103:2461–2469
    [Google Scholar]
  14. Toni M., Casewell M. W., Schito G. C. Reappraisal of the significance of multiply resistant urinary isolates of Proteus rettgeri. J Antimicrob Chemother 1980; 6:527–534
    [Google Scholar]
  15. Farmer J. J. Enterobacteriaceae: introduction and identification. In Murray P., Baron E., Pfaller M., Tenover F., Yolken R. (eds) Manual of clinical microbiology Washington, DC: American Society for Microbiology; 1995438–449
    [Google Scholar]
  16. Rather P. N., Orosz E., Shaw K. J., Hare R., Miller G. Characterization and transcriptional regulation of the 2′-N-acetyltransferase gene from Providencia stuartii. J Bacteriol 1993; 175:6492–6498
    [Google Scholar]
  17. Gu J. W., Neu H. C. In vitro activity of Dactimicin, a novel pseudodisaccharide aminoglycoside, compared with activities of other aminoglycosides. Antimicrob Agents Chemother 1989; 33:1998–2003
    [Google Scholar]
  18. Hawkey P. M., Penner J. L., Linton A. H., Hawkey C. A., Crisp J. L., Hinton M. Speciation, serotyping, antimicrobial sensitivity and plasmid content of Proteeae from the environment of calfrearing units in South West England. J Hyg 1986; 97:405–417
    [Google Scholar]
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