1887

Abstract

The effect of growth hormone (GH) on the release of IL-1α and IFN- from murine splenocytes was investigated. Their release from splenocytes activated by serovar Typhimurium lipopolysaccharide (LPS) 0.5γg/ml was increased by c. 65% in the presence of GH 100 pg/ml. With splenocytes activated by Typhimurium porins 5 μg/ml, GH increased the production of both IL-1α and IFN- by c. 56%. Polymyxin treatment abolished the cytokine-releasing activity of LPS but had no effect on the activity of the porin preparation.

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1996-07-01
2024-04-18
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