1887

Abstract

The effect of growth hormone (GH) on the release of IL-1α and IFN-γ from murine splenocytes was investigated. Their release from splenocytes activated by serovar Typhimurium lipopolysaccharide (LPS) 0.5γg/ml was increased by c. 65% in the presence of GH 100 pg/ml. With splenocytes activated by Typhimurium porins 5 μg/ml, GH increased the production of both IL-1α and IFN-γ by c. 56%. Polymyxin treatment abolished the cytokine-releasing activity of LPS but had no effect on the activity of the porin preparation.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-45-1-40
1996-07-01
2020-01-28
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-45-1-40
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error