a vaginal pathogen? Free

Abstract

The significance of as an aetiological agent in vaginitis was evaluated. A total of 6226 samples from women who presented with vaginal symptoms was examined. The presence of >10 leucocytes/high-power field (h.p.f.) was taken to be the criterion of active infection. was isolated from 10.1% of these samples. The isolation rates of other common pathogens such as spp., and spp. were 54.1%, 27.2% and 4.2%, respectively, in the same group of patients. In contrast, the isolation rates of these micro-organisms in the group of patients who had no infection (< 10 leucocytes/h.p.f.) were 4.2%, 38.3%, 33% and 0.5%, respectively. In the majority of samples from which was isolated, it was the sole pathogen isolated (83%) and its presence was associated with an inflammatory response in 80% of patients. Furthermore, the relative risk of vaginal infection with (2.38) in patients with purulent vaginal discharge was greater than that of spp. infection (1.41) and lower than that of spp. infection (8.32). These data suggest that in symptomatic women with microscopic evidence of inflammation should be considered a causative agent of vaginitis.

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1996-03-01
2024-03-29
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References

  1. Ross P. W. Group-B streptococcus — profile of an organism. J Med Microbiol 1984; 18:139–166
    [Google Scholar]
  2. Regan J. A., Cha S., James L. S. Premature rupture of membranes, preterm delivery, and group B streptococcal colonization of mothers. Am J Obstet Gynecol 1981; 141:184–186
    [Google Scholar]
  3. Boyer K. M., Gadzala C. A., Kelly P. D., Burd L. I., Gotoff S. P. Selective intrapartum chemoprophylaxis of neonatal group B streptococcal early-onset disease. II. Predictive value of prenatal cultures. J Infect Dis 1983; 148:802–809
    [Google Scholar]
  4. Schwartz B., Schuchat A., Oxtoby M. J., Cochi S. L., Hightower A., Broome C. V. Invasive group B streptococcal diseases in adults. A population-based study in metropolitan Atlanta. JAMA 1991; 266:1112–1114
    [Google Scholar]
  5. Farley M. M., Harvey R. C., Stull T. A population-based assessment of invasive disease due to group B streptococcus in nonpregnant adults. N Engl J Med 1993; 328:1807–1811
    [Google Scholar]
  6. Edwards M. S., Baker C. J. Streptococcus agalactiae (group B streptococcus). In Mandell G. L., Douglas R. G., Bennet J. E. (eds) Principles and practice in infectious diseases 3rd edn New York: Churchill Livingstone; 19901554–1563
    [Google Scholar]
  7. Wald E. R., Dashefsky B., Green M. Rapid detection of group B streptococci directly from vaginal swabs. J Clin Microbiol 1987; 25:573–574
    [Google Scholar]
  8. Colman G. Typing of Streptococcus agalactiae (Lancefield Group B). Eur J Clin Microbiol Infect Dis 1988; 7:226–231
    [Google Scholar]
  9. Fletcher R. H., Fletcher S. W., Wagner E. H. (eds) Clinical epidemiology — the essentials. Baltimore: Williams and Wilkins; 198291–105
    [Google Scholar]
  10. Eidelman A. I., Rudensky B., Turgeman D., Nubani N., Schimmel M. S., Isacsohn M. Epidemiology of group B streptococci colonization and disease in mothers and infants: update of ongoing 10-year Jerusalem study. Isr J Med Sci 1990; 26:71–73
    [Google Scholar]
  11. Forster U., Borkhardt H. L. [Vaginal streptococcus B colonization in pregnancy.]. Zentralbl Gynakol 1988; 110:174–178
    [Google Scholar]
  12. Visconti A., Orefici G., Notamicola A. M. Colonization and infection of mothers and neonates with group B streptococci in three Italian hospitals. J Hosp Infect 1985; 6:265–276
    [Google Scholar]
  13. Easmon C. S., Hastings J. G. M., Neill J., Bloxham B., Rivers R. P. A. Is group B streptococcal screening during pregnancy justified?. Br J Obstet Gynaecol 1985; 92:197–201
    [Google Scholar]
  14. Anthony B. F., Eisenstadt R., Carter J., Kim K. S., Hobel C. J. Genital and intestinal carriage of Group B streptococci during pregnancy. J Infect Dis 1981; 143:761–766
    [Google Scholar]
  15. Jensen N. E., Andersen B. L. The prevalence of group B streptococci in human urogenital secretions. Scand J Infect Dis 1979; 11:199–202
    [Google Scholar]
  16. Savarino A., Mattei R., Barsotti A., Bechi R., Saisi F., Lend F. [Hemolytic group B streptococcus in cervico-vaginal secretions.]. Quad Sclavo Diagn 1988; 24:185–188
    [Google Scholar]
  17. Catlin B. W. Gardnerella vaginalis: characteristics, clinical considerations, and controversies. Clin Microbiol Rev 1992; 5:213–237
    [Google Scholar]
  18. Kontnick C. M., Edberg S. C. Direct detection of group B streptococci from vaginal specimens compared with quantitative culture. J Clin Microbiol 1990; 28:336–339
    [Google Scholar]
  19. Gardner S. E., Yow M. D., Leeds L. J., Thompson P. K., Mason E. O., Clark D. J. Failure of penicillin to eradicate group B streptococcal colonization in the pregnant woman. A couple study. Am J Obstet Gynecol 1979; 135:1062–1065
    [Google Scholar]
  20. Tsakris A., Maniatis A. N. Inducible type of erythromycin resistance among group B streptococci isolated in Greece. J Antimicrob Chemother 1993; 31:177–178
    [Google Scholar]
  21. Kim K. S. Antimicrobial susceptibility of GBS. Antibiot Chemother 1985; 35:83–89
    [Google Scholar]
  22. Aronoff S. C., Laurent C., Jacobs M. R. In-vitro activity of erythromycin, roxithromycin and CP 62993 against common paediatric pathogens. J Antimicrob Chemother 1987; 19:275–276
    [Google Scholar]
  23. Von Recklinghausen G., Fischer W., Schmidt K., Ansorg R. Resistance of Streptococcus agalactiae to erythromycin. J Antimicrob Chemother 1989; 24:93
    [Google Scholar]
  24. Berkowitz K., Regan J. A., Greenberg E. Antibiotic resistance patterns of group B streptococci in pregnant women. J Clin Microbiol 1990; 28:5–7
    [Google Scholar]
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