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Volume 43, Issue 1

Iron supply of staphylococci and of micrococci by α-ketoacids Free

Abstract

Summary

Most of 232 strains of coagulase-negative staphylococci (CNS) belonging to 16 species, and nine strains of micrococci belonging to four species, could be distinguished by their growth on an iron-poor nutrient medium. α-Keto-/α-hydroxyacids, as primary metabolites, facilitated iron supply to CNS and micrococci under various iron-limited conditions, as detected by different bioassay methods. Twelve selected CNS strains and two micrococcal strains produced significant amounts of α-ketoacids in iron-poor liquid nutrient media. In particular, strains of and unable to grow on iron-poor media, produced high amounts of pyruvic acid and α-ketoglutaric acid. In bioassays, the selected CNS strains being siderophore indicator strains were fed with α-ketoacids at different levels of iron limitation. Strains able to grow under iron deprivation appeared to produce additional siderophores such as staphyloferrins under iron stress, α-Keto-/α-hydroxyacids may be additionally active in the iron supply of CNS and micrococci.

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  • Accepted:
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  • Published Online:
© J. MED. MICROBIOL. 1995
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1995-07-01
2024-04-19
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Iron supply of staphylococci and of micrococci by α-ketoacids
J. Med. Microbiol. 43, 26 (1995); https://doi.org/10.1099/00222615-43-1-26
/content/journal/jmm/10.1099/00222615-43-1-26
/content/journal/jmm/10.1099/00222615-43-1-26
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