%0 Journal Article %A Prevost, G. %A Couppie, P. %A Prevost, P. %A Gayet, S. %A Petiau, P. %A Cribier, B. %A Monteil, H. %A Piemont, Y. %T Epidemiological data on Staphylococcus aureus strains producing synergohymenotropic toxins %D 1995 %J Journal of Medical Microbiology, %V 42 %N 4 %P 237-245 %@ 1473-5644 %R https://doi.org/10.1099/00222615-42-4-237 %I Microbiology Society, %X Surmmary DNA hybridisation of 309 consecutive Staphylococcus aureus clinical isolates with oligonucleotide probes specific for genes encoding Panton-Valentine leucocidin (luk-PV) and y-haemolysin (hlg) revealed that 99% of randomly selected strains carried the hlg locus whereas only 2% harboured the luk-PV as well as the hlg loci. Only 1% of the strains did not possess either gene. In a clinical prospective study of independent S. aureus strains, 58 Panton-Valentine leucocidin (PVL)-producing isolates were shown to be responsible for primary skin infections, mainly furuncles (86 %). Phage susceptibility patterns and pulsed field gel electrophoresis (PFGE) profiles of DNA were shown to be polymorphic epidemiological markers of PVL-producing strains. In eight patients with recurrent furuncles, the PVL-producing strains isolated either from furuncles or from the anterior nares were considered to be identical in each based upon phage sensitivity profiles or PFGE patterns. %U https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-42-4-237