1887

Abstract

Summary

Immunoblotting sera from cases of or endocarditis against an extract from strain MUCOB 263 had identified three immunodominant antigenic bands at 190, 200 and 220 kDa. A lambda ZAPII DNA library was produced from the sheared genomic DNA of MUCOB 263 and six identical positive clones were identified when this library was screened with serum from a patient with endocarditis caused by a bacterium from the mutans group of streptococci. On subcloning and sequencing, a protein containing 1548 amino acids was identified with a 99·2% homology to the SpaA antigen of and 68·4% homology to the PAc antigen of

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/content/journal/jmm/10.1099/00222615-40-5-330
1994-05-01
2020-01-28
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-40-5-330
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