1887

Abstract

Summary

The effect of growth in iron-excess or iron-limitation conditions on the invasi veness for HeLa cells of HB101 carrying plasmid pRI203 which bears the invasion gene of was examined. Iron-limitation reduced adhesion and the number of organisms internalised by HeLa cells by about 100-fold. The reduced adhesion of iron-starved bacteria correlated with reduced hydrophobicity and the reduced invasiveness appeared to depend on the plasmid copy number, which was 3·5-fold less than in bacteria grown in iron excess.

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1994-04-01
2022-09-28
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