1887

Abstract

Summary

Incubation with type 12 was shown to lead to marked alterations of the fucose, galactose, and total hexose content of human immunoglobulin G (IgG). Immunological studies showed at least partial identity of this altered IgG and normal IgG. Streptococcal antigen was not found in the altered immunoglobulin. We suggest that if such alterations occurred , the altered immunoglobulin might become autoimmunogenic or might possess the biological properties of immune complexes and thus be of immunopathological significance in post-streptococcal glomerulonephritis.

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/content/journal/jmm/10.1099/00222615-4-4-535
1971-11-01
2019-10-18
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