1887

Abstract

SUMMARY

Colostrum-deprived and normally suckled piglets from normal sows and from sows immunised with an extract of O138:K81(B) were challenged with the same endotoxic extract preparation by the dermal, intravenous and oral routes. Reactions were more severe in piglets from immunised sows, and lesions were similar to those seen in field outbreaks of disease. It is postulated that such lesions may be immunological in origin, and that anaphylactic shock may be important in the pathogenesis of disease in baby piglets.

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1971-08-01
2024-04-23
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References

  1. Binns R. M. 1967; Bone marrow and lymphoid cell injection of the pig foetus resulting in transplantation tolerance or immunity, and immunoglobulin production. Nature, Lond 214:179
    [Google Scholar]
  2. Buxton A., Thomlinson J. R. 1961; The detection of tissue sensitizing antibodies toEscherichia coli in oedema disease, haemorrhagic gastro-enteritis and in normal pigs. Res. Vet. Sci 2:73
    [Google Scholar]
  3. Erskine R. G., Sojka W. J., Lloyd M. K. 1957; The experimental reproduction of a syndrome indistinguishable from oedema disease. Vet. Rec 69:301
    [Google Scholar]
  4. Gell P. G. H., Hinde Isobel T. 1954; Observations on the histology of the Arthus reaction and its relation to other known types of skin hypersensitivity. Int. Archs Allergy Appl. Immun 5:23
    [Google Scholar]
  5. Kim Y. B., Bradley S. G., Watson D. W. 1966; Ontogeny of the immune response. I. Development of immunoglobulins in germfree and conventional colostrum-deprived piglets. J. Immun 97:52
    [Google Scholar]
  6. Kohler E. M., Bohl E. H. 1966; Studies ofEscherichia coli in gnotobiotic pigs. I. Experimental reproduction of colibacillosis. Canad. J. Comp. Med 30:199
    [Google Scholar]
  7. Ohshima K., Miura S. 1961; Pathological study on an occurrence of swine edema disease in Iwata prefecture in 1959. Jap. J. Vet. Sci 23:111
    [Google Scholar]
  8. Shreeve B. J., Thomlinson J. R. 1970a; Hypersensitivity in young piglets: its relation to the pathogenesis ofEscherichia coli disease. J. Med. Microbiol 3:377
    [Google Scholar]
  9. Shreeve B. J., Thomlinson J. R. 1970b; Escherichia coli disease in the piglet. A pathological and bacteriological investigation. Br. Vet. J 126:444
    [Google Scholar]
  10. Shreeve B. J., Thomlinson J. R. 1971; Bacteriological and serological studies in preparturient sows. Br. Vet. J 127:57
    [Google Scholar]
  11. Stevens A. J. 1963; Coliform infections in the young pig and a practical approach to the control of enteritis. Vet. Rec 75:1241
    [Google Scholar]
  12. Thomlinson J. R., Buxton A. 1962; A comparison of experimental anaphylactic shock in guinea-pigs with naturally-occurring oedema disease and haemorrhagic gastroenteritis in pigs. Res. Vet. Sci 3:186
    [Google Scholar]
  13. Thomlinson J. R., Buxton A. 1963; Anaphylaxis in pigs and its relationship to the pathogenesis of oedema disease and gastro-enteritis associated withEscherichia coli . Immunology 6:126
    [Google Scholar]
  14. Timoney J. F. 1950; Oedema disease of swine. Vet. Rec 62:748
    [Google Scholar]
  15. Timoney J. F. 1956; Oedema disease of swine. Vet. Rec 68849
    [Google Scholar]
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