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Abstract
The MICs of fusidic acid and two sulphonamides for nine strains of Nocardia asteroides, two strains of N. caviae and one strain of N. blackwellii were studied by means of a plate-dilution technique. The median value for the MIC of fusidic acid, 2.5 fig per ml, compared very favourably with those of the sulphonamides, and fusidic acid may well have a part to play in the treatment of nocardiosis.
We would like to acknowledge the generous supply of fusidic acid by Leo Laboratories Limited, sulphadiazine by May & Baker Limited and sulphamethoxazole by the Wellcome Foundation. We are also very grateful to those mentioned in the text who supplied us with strains of Nocardia. Finally we wish to thank Dr J. C. J. Ives for helpful criticisms and advice.
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