1887

Abstract

Summary

Dissemination of from the site of carriage into the bloodstream and its localisation at a traumatised portion of a bone were studied in four categories of mice, viz., carrier hypersensitive, carrier nonhypersensitive, non-carrier hypersensitive, and non-carrier non-hypersensitive. The provocations used were a pyrogenic stimulus, produced by intraperitoneal injection of 0·1 ml of modified Haffkine plague vaccine, and controlled trauma to the right hind leg, either alone or in combination. It was observed that transient bacteriaemia occurred during periods of induced fever or as a sequel to trauma. It is of interest that 27 per cent. of the hypersensitive carrier mice as opposed to 2 per cent. of the non-hypersensitive carriers showed positive blood culture. Among the non-carrier mice, positive blood culture was obtained from 2·5 per cent. of the hypersensitive animals only. Significantly, localisation of at the injured bone was detectable in hypersensitive mice only.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-4-2-203
1971-05-01
2019-10-16
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-4-2-203
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error