1887

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Volume 38, Issue 4

Characteristics of an Avirulent Strain and its Virulence-Enhanced Variants Free

Abstract

Summary

The virulence of for 11-day-old chick embryos is associated with the ability to invade the chorio-allantoic membrane, to resist phagocytosis and to survive and proliferate . The pathogenicity of a well characterised avirulent strain was enhanced by passaging it intravenously and chorio-allantoically through chick embryos. The resulting isogenic variants had greatly increased ability to survive . In this study, the morphological and cell-surface characteristics of the avirulent parental strain were compared with those of the more virulent variants to determine whether pathogenicity was associated with one or more cell-surface constituents. Changes associated with the increased virulence of the two variants included alterations in cultural and cellular morphology, loss of flagella, expression of a new outer-membrane protein, alterations in cell-surface carbohydrates and decreases in cell-surface hydrophobicity.

  • Received:
  • Accepted:
  • Revised:
  • Published Online:
© Society for General Microbiology, 1993
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1993-04-01
2024-04-25
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Characteristics of an Avirulent Campylobacter Jejuni Strain and its Virulence-Enhanced Variants
J. Med. Microbiol. 38, 293 (1993); https://doi.org/10.1099/00222615-38-4-293
/content/journal/jmm/10.1099/00222615-38-4-293
/content/journal/jmm/10.1099/00222615-38-4-293
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