@article{mbs:/content/journal/jmm/10.1099/00222615-38-1-49, author = "Singh, D. V. and Sanyal, S. C.", title = "Haemagglutinating activity, serum sensitivity and enterotoxigenicity of Aeromonas spp.", journal= "Journal of Medical Microbiology", year = "1993", volume = "38", number = "1", pages = "49-53", doi = "https://doi.org/10.1099/00222615-38-1-49", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-38-1-49", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "Summary Of 97 isolates of Aeromonas spp. that were examined for haemagglutination (HA) and enterotoxigenicity, 35 were from clinical and 62 from environmental sources; 66 of them were also screened for sensitivity to normal human serum (NHS). HA was caused by 44 isolates (45%); it was unrelated to the source of the strain, but it was caused by a higher proportion of the isolates of A. hydrophila than of A. sobria or A. caviae. Of the haemagglutinating strains, 82% were enterotoxigenic, whereas most of the non-haemagglutinating strains were non-toxigenic when tested initially. All the latter became enterotoxin producers after serial passage through rabbit ileal loops, but without change in HA. Most (64%) of the isolates, including 68% of A. caviae (72% of clinical and 65% of environmental), were resistant to the bactericidal action of NHS. Most (92%) of the serum-sensitive strains were killed by activation of both the classical and alternate pathways of complement, the others only by the alternate pathway. Most (74%) of the serum-resistant strains caused fluid accumulation in the initial tests in ileal loops, regardless of species or source. Haemagglutinating and serum-resistant strains caused significantly more accumulation of fluid (p.0.05) than non-haemagglutinating and serum-sensitive strains. This study shows partial correlation between HA or serum sensitivity and enterotoxigenicity, but the properties are probably not genetically linked.", }