1887

Abstract

Summary

Monoclonal antibodies (MAbs) were produced to an outer-envelope preparation from () , the aetiological agent of swine dysentery. Three MAbs (isotype IgG1) were obtained. All three recognised a 16-kDa antigen that was common to most strains of of different serotypes but was absent from non-pathogenic, porcine intestinal spirochaetes. Immunofluorescence and immunogold labelling studies showed that the 16-kDa antigen was exposed on the surface of intact spirochaetes. The MAbs agglutinated freshly grown cultures of spirochaetes and inhibited growth of strains .

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1992-09-01
2022-05-17
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