RT Journal Article SR Electronic(1) A1 Mills, S. D. A1 Kuzniar, B. A1 Shames, B. A1 Kurjanczyk, L. A. A1 Penner, J. L.YR 1992 T1 Variation of the O antigen of Campylobacter jejuni in vivo JF Journal of Medical Microbiology, VO 36 IS 3 SP 215 OP 219 DO https://doi.org/10.1099/00222615-36-3-215 PB Microbiology Society, SN 1473-5644, AB Summary During the course of a clinical study on patients with campylobacteriosis, three consecutive isolates of Campylobacter jejuni from the same patient were sent for O-serotyping. Marked differences in the specificities of the O antigens of the isolates were observed between the first and third isolates when a passive haemagglutination assay system developed for serotyping C. jejuni was used. Differences in specificity were also demonstrated by immunoblots of lipopolysaccharides (LPS) from proteinase K-digested whole cells. The three isolates could not be distinguished either by restriction endonuclease analysis of chromosomal DNA, by gel electrophoresis of whole-cell proteins or by silver-stained LPS gels, thus providing evidence that they were of the same strain and that antigenic variation had occurred in vivo., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-36-3-215