1887

Abstract

Summary

A novel iron-binding compound was identified in ethyl acetate extracts of the supernates from cultures. This compound, named azurechelin, was produced by 88% of strains isolated from the respiratory tract. Production of azurechelin was regulated by the iron concentration in the culture medium. Azurechelin enhanced the growth of in a medium containing transferrin 200 mg/L. Azurechelin released iron from transferrin in an equilibrium dialysis assay, suggesting that it could compete with transferrin for iron. Azurechelin could also stimulate iron uptake by . This siderophore appeared to have a novel structure with neither the typical characteristics of catechol nor of hydroxamate compounds.

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/content/journal/jmm/10.1099/00222615-36-3-184
1992-03-01
2019-09-22
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-36-3-184
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