1887

Abstract

Summary

Twenty isolates of from cases of typhoid during the 1989–1990 epidemic in Calcutta were examined. Most isolates (84% of all isolates in the epidemic) were resistant to chloramphenicol, ampicillin, tetracycline and streptomycin but were sensitive to nalidixic acid and ciprofloxacin. Plasmids of 120 kb and 14 kb were identified amongst the multi-drug resistant isolates of However, there was no plasmid in the antibiotic-sensitive isolates. The 120-kb plasmid was transferable and transconjugants were resistant to chloramphenicol, ampicillin, tetracycline and streptomycin. Restriction endonuclease analysis patterns after RI digestion of the 120-kb antibiotic-resistance plasmids from the isolates and transconjugants were similar.

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/content/journal/jmm/10.1099/00222615-34-3-149
1991-03-01
2022-01-25
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References

  1. Anand A. C., Kataria V. K., Singh W., Chatterjee S. K. Epidemic multiresistant enteric fever in eastern India. Lancet 1990; 1:352
    [Google Scholar]
  2. Marmion D. E. The treatment of typhoid fever with chloram phenicol; a clinical study of 330 cases of enteric fever treated in Egypt. Trans R Soc Trop Med Hyg 1952; 46:619–638
    [Google Scholar]
  3. Cook A. T., Marmion D. E. Chloromycetin in treatment of typhoid fever. Lancet 1949; 2:975–979
    [Google Scholar]
  4. Woodward T. E., Smadel J. E., Ley H. L. Chloramphenicol and other antibiotics in the treatment of typhoid fever and typhoid carriers. J Clin Invest 1950; 29:87–99
    [Google Scholar]
  5. Knight V., Sanchez F. R., Sanchez A. R., Shultz S., McDermott W. Antimicrobial therapy in typhoid. Arch Intern Med 1950; 85:44–82
    [Google Scholar]
  6. Naylor G. R. E. Incubation period and other features of food-borne and water-borne outbreaks of typhoid fever in relation to pathogenesis and genetics of resistance. Lancet 1983; 1:864–866
    [Google Scholar]
  7. DeVries R. R. P., Meerakhan P., Bernini L. F., Van Loghem E., Van Rood J. J. Genetic control of survival in epidemics. J Immunogenet 1979; 6:271–287
    [Google Scholar]
  8. Maskel D. J., Hormaeche C. E. Relapse following cessation of antibiotic therapy for mouse typhoid in resistant and susceptible mice infected with salmonellae of differing virulence. J Infect Dis 1985; 152:1044–1049
    [Google Scholar]
  9. Macrina F. L., Kopecko D. J., Jones K. R., Ayers D. J., McCowen S. M. A multiple plasmid-containing Escherichia coli strain; convenient source of size reference plasmid molecules. Plasmid 1978; 1:417–420
    [Google Scholar]
  10. Kado C. I., Liu S. T. Rapid procedure for detection and isolation of large and small plasmids. J Bacterial 1981; 145:1365–1373
    [Google Scholar]
  11. Maniatis T. E., Fritsch E. F., Sambrook J. Molecular cloning: a laboratory manual Cold Spring Harbor, NY, Cold Spring Harbor Laboratory; 1982
    [Google Scholar]
  12. Palchaudhuri S., Kumar R., Sen D. Molecular epidemiology of plasmid patterns in Shigella dysenteriae type 1 obtained from an outbreak in West Bengal (India). FEMS Microbiol Lett 1985; 30:187–191
    [Google Scholar]
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