1887

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Volume 34, Issue 1

Detection of HSV-1 DNA in patients with Behcet’s syndrome and in patients with recurrent oral ulcers by the polymerase chain reaction Free

Abstract

Summary

The polymerase chain reaction was used to detect HSV-1 DNA in genomic DNA extracted from peripheral blood leucocytes, in patients with Behcet’s syndrome (BS), patients with recurrent oral ulcers and normal healthy controls. A 211-bp HSV-1 DNA fragment was found in a significant number of patients with BS (p <0.02). Serum anti-HSV-1 antibodies were also found in a higher proportion of patients with BS (p <0.02) than in healthy controls. However, virus-specific DNA was not detected in biopsy samples taken from oral ulcers in patients with BS.

  • Received:
  • Accepted:
  • Published Online:
© J. MED. MICROBIOL. 1991
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1991-01-01
2024-04-20
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Detection of HSV-1 DNA in patients with Behcet’s syndrome and in patients with recurrent oral ulcers by the polymerase chain reaction
J. Med. Microbiol. 34, 39 (1991); https://doi.org/10.1099/00222615-34-1-39
/content/journal/jmm/10.1099/00222615-34-1-39
/content/journal/jmm/10.1099/00222615-34-1-39
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