1887

Abstract

The conditions required to kill with nalidixic acid, ciprofloxacin, norfloxacin or ofloxacin were determined in nutrient broth and in phosphate-buffered saline. They were found to be similar to the conditions required for these 4-quinolones to kill Bacterial RNA synthesis and bacterial cell division were essential for the bactericidal activity of nalidixic acid but all three fluoroquinolones were bactericidal against non-dividing However, as with , bacterial RNA synthesis was essential for the bactericidal activity of norfloxacin though this was not required to kill with ciprofloxacin or ofloxacin.

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/content/journal/jmm/10.1099/00222615-32-3-211
1990-07-01
2019-10-16
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-32-3-211
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