1887

Abstract

Bacteria were grown from 63 (69%) of 91 specimens from necrotic tumours in 63 patients. Of the tumours, 14 were abdominal, 5 pelvic, 23 of the head and neck, 4 of the lungs, 4 mediastinal, 2 lymphatic, 3 of the breast, and 8 were miscellaneous. Aerobic or facultatively anaerobic bacteria only were present in 12 (19%) specimens, anaerobes only in 10 (16%), and mixed aerobic and anaerobic bacteria in 41 (65%). A total of 83 anaerobic and 47 aerobic and facultatively anaerobic bacteria were isolated. The predominant anaerobic bacteria were spp. (36 isolates), and anaerobic cocci (21) and (22). The aerobic and facultatively anaerobic bacteria most frequently isolated were , a-haemolytic streptococci, (seven isolates each), and (five isolates each). These data demonstrate that infection of tumours is usually polymicrobial.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-32-3-207
1990-07-01
2024-04-18
Loading full text...

Full text loading...

/deliver/fulltext/jmm/32/3/medmicro-32-3-207.html?itemId=/content/journal/jmm/10.1099/00222615-32-3-207&mimeType=html&fmt=ahah

References

  1. Alpem R J., Dowell V R. 1969; Clostridum septicum infection and malignancy. Journal of the American Medical Association 209:385–388
    [Google Scholar]
  2. Altemier W A. 1942; The pathogenicity of the bacteria of appendicitis peritonitis; experimental study. Surgery 11:374–384
    [Google Scholar]
  3. Ashby E C., Rees M., Dowding C H. 1978; Prophylaxis against systemic infection after transrectal biopsy for suspected prostatic carcinoma. British Medical Journal ii 1263–1264
    [Google Scholar]
  4. Bodey G P. 1986; Infection in cancer patients. A continuing association. American Journal of Medicine 81:Suppl 1A1126
    [Google Scholar]
  5. Brook I. 1985; Enhancement of growth of aerobic and facultative bacteria in mixed infections with Bacteroides species. Infection and Immunity 50:929–931
    [Google Scholar]
  6. Brook I. 1989; Pediatric anaerobic infection: diagnosis and management. C. V. Mosby Co., St Louis, MO.
    [Google Scholar]
  7. Brook I., Hunter V., Walker R I. 1984; Synergistic effect of Bacteroides, Clostridium, Fusobacterium, anaerobic cocci, and aerobic bacteria on mortality and induction of subcutaneous abscesses in mice. Journal of Infectious Diseases 149:924–928
    [Google Scholar]
  8. Cabrera A., Tsukada Y., Pickren J W. 1965; Clostridial gas gangrene and septicemia in malignant disease. Cancer 18:800–806
    [Google Scholar]
  9. Caya J G. et al. 1986; Clostridial septicemia complicating the course of leukemia. Cancer 57:2045–2048
    [Google Scholar]
  10. Hite K E., Locke M., Hesseltine H C. 1949; Synergism in experimental infections with nonsporulating anaerobic bacteria. Journal of Infectious Diseases 84:1–9
    [Google Scholar]
  11. Klastersky J., Coppens L., Mombelli G. 1979; Anaerobic infection in cancer patients: comparative evaluations of clindamycin and cefoxitin. Antimicrobial Agents and Chemotherapy 16:366–371
    [Google Scholar]
  12. Klastersky J., Husson M., Weerts-Ruhl D., Daneau D. 1977; Anaerobic wound infections in cancer patients: comparative trial of clindamycin, tinidazole and doxycycline. Antimicrobial Agents and Chemotherapy 12:563–570
    [Google Scholar]
  13. Lagast H., Klastersky J. 1982; Anaerobic infections in cancer patients—a retrospective analysis of clindamycin, tinidazole, doxycycline, cefoxitin and moxalactam. Infection 10:144–148
    [Google Scholar]
  14. Lagast H., Meunier-Carpentier F., Klastersky J. 1982; Moxalactam treatment of anaerobic infections in cancer patients. Antimicrobial Agents and Chemotherapy 22:604–610
    [Google Scholar]
  15. Lennette E H., Balows A., Hausler W J., Shadomy H J. eds 1985 Manual of clinical microbiology. , 4th edn. American Society for Microbiology; Washington, DC:
    [Google Scholar]
  16. Malmgren R A., Flanigan C C. 1955; Localization of the vegetative form of Clostridium tetani in mouse tumours following intravenous spore administration. Cancer Research 15:473–478
    [Google Scholar]
  17. Rotimi V O., Durosinmi-Etti F A. 1984; The bacteriology of infected malignant ulcers. Journal of Clinical Pathology 37:592–595
    [Google Scholar]
  18. Sinkovics J G., Smith J P. 1970; Septicemia with bacteroides in patients with malignant disease. Cancer 25:663–671
    [Google Scholar]
  19. Sutter V L., Citron D M., Edelstein M A C., Finegold S M. 1985 Wadsworth anaerobic bacteriology manual. , 4th edn. Star Publishing Co; Belmont, CA:
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-32-3-207
Loading
/content/journal/jmm/10.1099/00222615-32-3-207
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error