1887

Abstract

Summary

To investigate changes in the gonococcal population over time, the plasmid content, serotype and auxotype have been determined for strains of penicillinase-producing (PPNG) isolated from patients attending the Praed Street Clinic for Sexually Transmitted Diseases between 1978 and 1987. Three distinct changes have been identified: (i) in the main plasmid type, from PPNG with the 3.2-Mda plasmid before 1982 to strains with the 4.4-Mda plasmid between 1982 and 1985; (ii) the decline during this time of strains also carrying the 24.5-Mda conjugal plasmid; (iii) the re-emergence of PPNG with the 3.2-Mda plasmid in 1986. The three typing methods used have identified eight clusters of strains which have been prevalent in different years between 1978 and 1987.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-30-4-239
1989-12-01
2022-01-16
Loading full text...

Full text loading...

/deliver/fulltext/jmm/30/4/medmicro-30-4-239.html?itemId=/content/journal/jmm/10.1099/00222615-30-4-239&mimeType=html&fmt=ahah

References

  1. Phillips I. 1976; β-lactamase-producing, penicillin-resistant gon ococcus. Lancet 2:656–657
    [Google Scholar]
  2. Percival A., Rowlands J., Corkhill J. E. 1976; Penicillinase-producing gonococci in Liverpool. Lancet 2:1379–1382
    [Google Scholar]
  3. Centers for Disease Control 1976; Penicillinase-producing Neis seria gonorrhoeae. Morbidity and Mortality Weekly Report 25:261
    [Google Scholar]
  4. Ashford W. A., Golash R. G., Hemming V. G. 1976; Penicillinase-producing Neisseria gonorrhoeae. Lancet 2:657–658
    [Google Scholar]
  5. Perine P. L., Thornsberry C., Schalla W. 1977; Evidence for two distinct types of penicillinase-producing Neisseria gonorrhoeae. Lancet 2:993–995
    [Google Scholar]
  6. van Embden J. D. A., Dessens-Kroon M., van Klingeren B. 1985; A new β-lactamase plasmid in Neisseria gonorrhoeae. J Antimicrob Chemother 15:247–250
    [Google Scholar]
  7. Yeung K.-H., Dillon J. R., Pauze M., Wallace E. 1986; A novel 4–9-kilobase plasmid associated with an outbreak of penicillinase-producing Neisseria gonorrhoeae. J Infect Dis 153:1162–1165
    [Google Scholar]
  8. Gouby A., Bourg G., Ramuz M. 1986; Previously undescribed 6–6-kilobase R plasmid in penicillinase-producing Neisseria gonorrhoeae. Antimicrob Agents Chemother 29:1095–1097
    [Google Scholar]
  9. Roberts M., Falkow S. 1977; Conjugal transfer of R plasmids in Neisseria gonorrhoeae. Nature 266:630–631
    [Google Scholar]
  10. PHLS Communicable Disease Report 1987; Sexually trans mitted disease in Britain; 1985. No. 45 3–6
  11. Ison C. A., Gedney J., Harris J. R. W., Easmon C. S. F. 1986; Penicillinase producing gonococci: a spent force?. Genitourin Med 62:302–307
    [Google Scholar]
  12. Knapp J. S., Tam M. R., Nowinski R. C., Holmes K. K., Sandstrom E. G. 1984; Serological classification of Neisseria gonorrhoeae with use of monoclonal antibodies to gonococcal outer membrane protein I. J Infect Dis 150:44–48
    [Google Scholar]
  13. Tam M. R., Buchanan T. M., Sandstrom E. G. 1982; Serological classification of Neisseria gonorrhoeae with monoclonal antibodies. Infect Immun 36:1042–1053
    [Google Scholar]
  14. Birnboim H. C., Doly J. 1979; A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acid Res 7:1513–1523
    [Google Scholar]
  15. Woodford N., Bindayna K. M., Easmon C. S. F., Ison C. A. 1989; Associations between serotype and susceptibility to antibiotics of Neisseria gonorrhoeae. Genitourin Med 65:86–91
    [Google Scholar]
  16. Catlin B. W. 1973; Nutritional profiles for Neisseria gonorrhoeae, Neisseria meningitidis and Neisseria lactamica in chemically defined media and the use of growth requirements for gonococcal typing. J Infect Dis 128:178–194
    [Google Scholar]
  17. Copley C. G., Egglestone S. I. 1983; Auxotyping of Neisseria gonorrhoeae isolated in the United Kingdom. J Med Microbiol 16:295–302
    [Google Scholar]
  18. Zenilman J. M., Whittington W. L., Frazier D., Rice R. J., Knapp J. S. 1988; Penicillinase-producing Neisseria gonorrhoeae in Dade County, Florida: phenotypic characterization of isolates from 1983, 1984 and 1986. Sex Transm Dis 15:158–163
    [Google Scholar]
  19. Ansink-Schipper M. C., Bygdeman S. M., van Klingeren B., Sandstrom E. G. 1988; Serovars, auxotypes and plasmid profiles of PPNG strains with Asian type plasmid isolated in Amsterdam. Genitourin Med 64:152–155
    [Google Scholar]
  20. van Klingeren B., Ansink-Schipper M. C., Dessens- Kroon M., Verheuvel M. 1985; Relationship between auxotype, plasmid pattern and susceptibility to antibiotics in penicillinase-producing Neisseria gonorrhoeae. J Antimicrob Chemother 16:143–147
    [Google Scholar]
  21. van Klingeren B., van Wijngaarden L. J., Dessens- Kroon M., van Embden J. D. A. 1983; Penicillinase producing gonococci in the Netherlands in 1981. J Antimicrob Chemother 11:15–20
    [Google Scholar]
  22. Bygdeman S. M.Polyclonal and monoclonal antibodies applied to the epidemiology of gonococcal infection In Young H., MacMillan A. (eds) Immunological diagnosis of sexually transmitted disease New York: Marcel Dekker Inc; 1987 117–165
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-30-4-239
Loading
/content/journal/jmm/10.1099/00222615-30-4-239
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error