1887

Abstract

SUMMARY

The clinical, morphological, biochemical and bacteriological characteristics of two methods for inducing a cholera-like condition in rabbits were evaluated. The infection in suckling rabbits was considered analogous in all essential respects to the natural disease in man, and the infection in ileal loops of adult rabbits duplicated the local pathology closely until excessive luminal pressure introduced artefacts. It appears that the loop method is better suited for immunological studies, but that the baby-rabbit infection will give more information on host-parasite interactions. An enterotoxin reproducing the manifestations of cholera was demonstrated.

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1970-08-01
2021-10-28
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