strains isolated from the urine of 111 pregnant women with significant asymptomatic bacteriuria were studied. Sixty per cent. of the 235 smooth strains isolated were successfully grouped in agglutination tests with antisera to ten 6-groups. Groups O2, O4, O6 and O75 accounted for the majority of the primary and recurrent isolates. Fifty-four women with initial infections due to a strain of a known O-group were treated and examined monthly until delivery. Over half of these 54 women failed to respond to therapy and 14 of them continued, in spite of further chemotherapy, to excrete bacteria of the same O-group for periods up to 30 wk.


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