A novel replicating agent isolated from the human intestinal tract having characteristics shared with Creutzfeldt-Jakob and related agents

References

1. Alper T., Haig D. A., Clarke M. C. 1966; The exceptionally small size of the scrapie agent. Biochemical and Biophysical Research Communications 22:278–284
   [Google Scholar]
2. Alper T., Cramp W. A., Haig D. A., Clarke M. C. 1967; Does the agent of scrapie replicate without nucleic acid?. Nature 214:764–766
   [Google Scholar]
3. Alper T., Haig D. A., Clarke M. C. 1978; The scrapie agent:evidence against its dependence for replication on intrinsic nucleic acid. Journal of General Virology 41:503–516
   [Google Scholar]
4. Bignami A., Parry H. B. 1971; Aggregation of 35-nanometer particles associated with neuronal cytopathic changes in natural scrapie. Science 171:389–390
   [Google Scholar]
5. Bockman J. M., Kingsbury D. T., McKinley M. P., Brendheim P. E., Prusiner S. B. 1985; Creutzfeldt-Jakob disease prion proteins in human brains. New England Journal of Medicine 312:73–78
   [Google Scholar]
6. Brown P. 1982a; Chemical disinfection of Creutzfeldt-Jakob disease virus. New England Journal of Medicine 306:1279–1282
   [Google Scholar]
7. Brown P., Rohwer R. G., Green E. M., Gajdusek D. C. 1982b; Effect of chemicals, heat, and histopathologic processing on high-infectivity hamster-adapted scrapie virus. Journal of Infectious Diseases 145:683–687
   [Google Scholar]
8. Brown P., Rohwer R. G., Gajdusek D. C. 1986; Newer data on the inactivation of Scrapie virus or Creutzfeldt-Jakob disease virus in brain tissue. Journal of Infectious Diseases 153:1145–1148
   [Google Scholar]
9. Butzow J. J., Eichhom G. L. 1975; Different susceptibility of DNA and RNA to cleavage by metal ions. Nature 254:358–359
   [Google Scholar]
10. Connors L. H., Shirahama T., Skinner M., Fenves A., Cohen A. S. 1985; In vitro formation of amyloid fibrils from intact ß 2-microglobulin. Biochemical and Biophysical Research Communications 131:1063–1068
    [Google Scholar]
11. Gajdusek D. C. 1977; Unconventional viruses and the origin and disappearance of kuru. Science 197:943–960
    [Google Scholar]
12. Gajdusek D. C. 1977; Precaution in medical care of, and in handling materials from, patients with transmissible virus dementia (Creutzfeldt-Jakob disease). New England Journal of Medicine 297:1253–1258
    [Google Scholar]
13. Gibbs C. T., Gajdusek D. C., Latarjet R. 1978; Unusual resistance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie. Proceedings of the National Academy of Science of the USA 75:6268–6270
    [Google Scholar]
14. Glenner G. G., Ein D., Eanes E. D., Bladen H. A., Terry W., Page D. L. 1971; Creation of “amyloid” fibrils from Bence Jones Protein in vitro. Science 174:712–714
    [Google Scholar]
15. Kimberlin R. H. 1982; Scrapie agent:prions or virinos?. Nature 297:107–108
    [Google Scholar]
16. Kochetkov N. K., Budowsky E. I. 1969; The chemical modification of nucleic acids. Progress in Nucleic Acid Research and Molecular Biology 9:403–438
    [Google Scholar]
17. Marsh R. F., Malone T. G., Semancik J. S., Lancaster W. D., Hanson R. P. 1978; Evidence for an essential DNA component in the scrapie agent. Nature 275:146–147
    [Google Scholar]
18. McKinley M. P., Masiarz F. R., Prusiner S. B. 1981; Reversible chemical modification of the scrapie agent. Science 214:1259–1261
    [Google Scholar]
19. McKinley M. P., Braunfeld M. B., Bellinger C. G., Prusiner S. B. 1986; Molecular characteristics of prion rods purified from scrapie-infected hamster brains. Journal of Infectious Diseases 154:110–120
    [Google Scholar]
20. Oesch B. 1985; A cellular gene encodes scrapie PrP 27–30 protein. Cell 40:735–746
    [Google Scholar]
21. Pattison I. H. 1965; Resistance of the scrapie agent to formalin. Journal of Comparative Pathology 75:159–164
    [Google Scholar]
22. Prusiner S. B. 1982; Novel proteinaceous infectious particles cause scrapie. Science 216:136–144
    [Google Scholar]
23. Prusiner S. B. 1984; Some speculation about prions, amyloid and Alzheimer’s disease. New England Journal of Medicine 310:661–663
    [Google Scholar]
24. Prusiner S. B. 1987; Prions and neurodegenerative diseases. New England Journal of Medicine 317:1571–1581
    [Google Scholar]
25. Prusiner S. B., Hadlow W. J., Eklund C. M., Race R. E., Cochran S. P. 1978a; Sedimentation characteristics of the scrapie agent from murine spleen and brain. Biochemistry 17:4987–4992
    [Google Scholar]
26. Prusiner S. B. 1978b; Partial purification and evidence for multiple molecular forms of the scrapie agent. Biochemistry 17:4993–4999
    [Google Scholar]
27. Prusiner S. B. 1980a; Experimental scrapie in the mouse:electrophoretic and sedimentation properties of the partially purified agent. Journal of Neurochemistry 35:574–582
    [Google Scholar]
28. Prusiner S. B., Groth D. F., Cochran S. P., Masiarz F. R., McKinley M. P., Martinez H. M. 1980b; Molecular properties, partial purification and assay by incubation period measurements of the hamster scrapie agent. Biochemistry 19:4883–4891
    [Google Scholar]
29. Prusiner S. B., Groth D. F., McKinley M. P., Cochran S. P., Bowman K. A., Kasper K. C. 1981; Thiocyanate and hydroxyl ions inactivate the scrapie agent. Proceedings of the National Academy of Science of the USA 78:4606–4610
    [Google Scholar]
30. Prusiner S. B., Bolton D. C., Groth D. F., Bowman K. A., Cochran S. P., McKinley M. P. 1982; Further purification and characterization of scrapie prions. Biochemistry 21:6942–6950
    [Google Scholar]
31. Prusiner S. B. 1983; Scrapie prions aggregate to form amyloid-like birefringent rods. Cell 35:349–358
    [Google Scholar]