1887

Abstract

Surmmary

Immunologically potent RNA-protein extracted from strain H37Ra, when entrapped in phosphatidylcholine multilamellar liposomes and injected into mice, induced both cellular and humoral immune responses. Significant protection against infection with H37Rv was also induced in the immunised mice, as monitored by (i) higher survival rates, (ii) decreased viable counts of H37Rv in lungs, livers and spleens, (iii) lower lung density, and (iv) lower root specific lung weight, in comparison with a control group of unimmunised mice.

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/content/journal/jmm/10.1099/00222615-29-2-131
1989-06-01
2019-12-08
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-29-2-131
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