1887

Abstract

SUMMARY

Monoclonal antibodies directed to six separate antigen molecules of have been tested in an antigen-capture assay based on combined use of polyclonal (“capture”) and monoclonal (“detector”) antibody reagents. This approach provides a potentially versatile, sensitive and specific assay for detection and relative quantitation of antigens. Characterisation of monoclonal antibodies to mycobacterial lipoarabinomannan (LAM-B) by the antigen-capture assay indicates that some of the antigenic determinants present on LAM-B from may be either absent altogether or present at much lower concentrations on the corresponding LAM-B structure from .

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/content/journal/jmm/10.1099/00222615-28-3-157
1989-03-01
2022-05-28
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