1887

Abstract

Summary

A receptor binding the Fc region of equine immunoglobulin G (IgG) has been isolated from a heat-extracted preparation of a clinical isolate of . This Fc receptor has a M of 45 x 10 and was occasionally seen as an apparent trimer of M 130 x 10. Antibodies prepared in horses against the receptor could be adsorbed to and eluted from whole live bacteria, confirming the surface location of this protein. Another 11 isolates of from horses with pneumonia, abscesses or endometritis were tested for Fc-receptor activity. Although the M of the Fc receptors varied among isolates, their antigenicity was conserved. Thus, the Fc receptor is an attractive candidate for application in the diagnosis of, or protection against, infections with .

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1989-02-01
2022-05-26
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