RT Journal Article SR Electronic(1) A1 Umeki, S.YR 1989 T1 Age-dependent changes in protease and elastase production in cultures of Pseudomonas aeruginosa JF Journal of Medical Microbiology, VO 28 IS 2 SP 109 OP 112 DO https://doi.org/10.1099/00222615-28-2-109 PB Microbiology Society, SN 1473-5644, AB Summary The intracellular and extracellular protease and elastase contents of Pseudomonas aeruginosa were studied in relation to the age of the culture. The intracellular protease and elastase content of the organisms decreased as the culture grew older, whereas extracellular protease and elastase greatly increased 24 h after incubation commenced, suggesting that host tissue injury by P. aeruginosa infection may increase in proportion to the duration of tissue colonisation., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-28-2-109