@article{mbs:/content/journal/jmm/10.1099/00222615-27-2-141, author = "Brahmadathan, K. N. and Koshi, Grace", title = "Use of enzymes in typing group A β-haemolytic streptococci", journal= "Journal of Medical Microbiology", year = "1988", volume = "27", number = "2", pages = "141-144", doi = "https://doi.org/10.1099/00222615-27-2-141", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-27-2-141", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "Summary A series of 698 strains of group A β-haemolytic streptococci (GAS) isolated from cildren with streptococcal pyoderma was tested for production of serum opacity factor (OF)and nicotinamide adenine dinucleotide glycohydrolase (NADase). OF was produced by 37% of strains and 40% produced NADase. Classification based on various combinations of OF and NADase reactions showed that 58% belonged to enzyme group e1 and 34% to e2. Correlation with T and M types showed the possible use of this means of classification as an epidemiological marker for GAS. The specificity of such a system in the further classification of various T types of GAS in epidemiological studies, in the light of antigenic variation among M types, is described.", }