1887

Abstract

SUMMARY

The pathogenicity of 20 strains belonging to nine bacterial species isolated from acute dentoalveolar abscesses was assessed individually and in two species combinations by subcutaneous inoculation of mice. Infections were produced by all the bacteria although variations were seen both in the type of lesion produced and the subsequent recovery of viable bacteria. Anaerobic gram-negative bacilli were recovered more often (p<0.05) at high concentrations (10–10 cfu/ml) and produced a localised abcess with peripheral necrosis more frequently (p<0.001) than either or anaerobic gram-positive cocci. Lesions induced by a combination of bacteria comprising an anaerobic gram-negative bacillus and any other species yielded both strains at high concentration more often (p<0.001) than a combination comprising anaerobic gram-positive cocciand . It is concluded that anaerobic gram-negative bacilli are major pathogens in acute dentoalveolar abscesses.

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1988-10-01
2022-07-02
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References

  1. Brook I. 1986; Isolation of capsulate anaerobic bacteria from orofacial abscesses. Journal of Medical Microbiology 22:171–174
    [Google Scholar]
  2. Brook I., Walker R. I. 1984; Pathogenicity of anaerobic grampositive cocci. Infection and Immunity 45:320–324
    [Google Scholar]
  3. Brook I., Walker R. I. 1986; The relationship between Fusobacterium species and other flora of mixed infection. Journal of Medical Microbiology 21:93–100
    [Google Scholar]
  4. Brook I., Gillmore J. D., Coolbaugh J. C., Walker R. I. 1983; Pathogenicity of encapsulated Bacteroides melaninogenicus group, B oralis and B. ruminicola subsp. brevis in abscesses in mice. Journal of Infection 7:218–226
    [Google Scholar]
  5. Heimdahl A., von Konow L., Satoh T., Nord C. E. 1985; Clinical appearance of orofacial infections of odontogenic origin in relation to microbiological findings. Journal of Clinical Microbiology 22:299–302
    [Google Scholar]
  6. Jones G. R., Gemmell C. G. 1986; Effects of Bacteroides asaccharolyticus cells and B fragiis surface components on serum opsonisation and phagocytosis. Journal of Medical Microbiology 22:225–229
    [Google Scholar]
  7. Kastelein P., van Steenbergen T. J. M., Bras J. M., DeGraaff J. 1981; An experimentally induced phlegmonous abscess by a strain of Bacteroides gingivalis in guinea pigs and mice. Antonie van Leeuwenhoek 47:1–9
    [Google Scholar]
  8. Lewis MacFarlane T. W., McGowan D. A. 1986; Quantitative bacteriology of acute dento-alveolar abscesses. Journal of Medical Microbiology 21:101–104
    [Google Scholar]
  9. MacDonald J. B., Socransky S. S., Gibbons R. J. 1963; Aspects of the pathogenesis of mixed anaerobic infections of mucous membranes. Journal of Dental Research 42: Suppl 1529544
    [Google Scholar]
  10. Okuda K., Takazoe I. 1973; Antiphagocytic effects of the capsular structure of a pathogenic strain of Bacteroides melaninogenicus. Bulletin of Tokyo Dental College 14:99–104
    [Google Scholar]
  11. Pancholi V., Ayyagari A. S., Agarwal K. C. 1985; Experimentally induced subcutaneous infection by black-pigmented Bacteroides species in rats. Journal of Infection 11:131–137
    [Google Scholar]
  12. Socransky S. S. 1977; Microbiology of periodontal disease— present status and future considerations. Journal of Perio-dontology 48:497–504
    [Google Scholar]
  13. Socransky S. S., Gibbons R. J. 1965; Required role of Bacteroides melaninogenicus in mixed anaerobic infections. Journal of Infectious Diseases 115:247–253
    [Google Scholar]
  14. Sundqvist G. K., Eckerbom M. I., Larson A. P., Sjogren U. T. 1979; Capacity of anaerobic bacteria from nectrotic dental pulps to induce purulent infections. Infection and Immunity 25:685–693
    [Google Scholar]
  15. Takazoe I., Nakamura T. 1971; Experimental mixed infection by human gingival crevice material. Bulletin of Tokyo Dental College IT85–93
    [Google Scholar]
  16. Van derVelden U., van Winkelhoff A. J., Abbas F., DeGraaff J. 1986; The habitat of periodontopathic microorganisms. Journal of Clinical Periodontology 13:243–248
    [Google Scholar]
  17. VanSteenbergen T. J. M., Kastelein P., Touw J. J. A., DeGraaff J. 1982; Virulence of black-pigmented Bacteroides strains from periodontal pockets and other sites in experimentally induced skin lesions in mice. Journal ofPeriodontal Research 17:41–49
    [Google Scholar]
  18. VanSteenbergen T. J. M., van Winkelhoff A. J., DeGraaff J. 1984; Pathogenic synergy: mixed infections in the oral cavity. Antonie van Leeuwenhoek 50:789–798
    [Google Scholar]
  19. Ward J. B., Berkeley R. C. W. 1981; The microbial cell surface and adhesion. In Berkeley R. C. W. (eds) Microbial adhesion to surfaces Ellis Horwood Limited; Chichester: pp 47–66
    [Google Scholar]
  20. Williams B. L., McCann G. F., Schoenknecht F. D. 1983; Bacteriology of dental abscesses of endodontic origin. Journal of Clinical Microbiology 18:770–774
    [Google Scholar]
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